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Fusion gene ID: 24710 |
FusionGeneSummary for NPIPB7_ATP10B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NPIPB7_ATP10B | Fusion gene ID: 24710 | Hgene | Tgene | Gene symbol | NPIPB7 | ATP10B | Gene ID | 440350 | 23120 |
| Gene name | nuclear pore complex interacting protein family member B7 | ATPase phospholipid transporting 10B (putative) | |
| Synonyms | A-575C2.4|A-761H5.5|NPIPL1 | ATPVB | |
| Cytomap | 16p12.1 | 5q34 | |
| Type of gene | pseudo | protein-coding | |
| Description | nuclear pore complex-interacting protein-like 1 | probable phospholipid-transporting ATPase VBATPase, class V, type 10BP4-ATPase flippase complex alpha subunit ATP10B | |
| Modification date | 20180329 | 20180523 | |
| UniProtAcc | O75200 | O94823 | |
| Ensembl transtripts involved in fusion gene | ENST00000452313, | ENST00000327245, ENST00000518411, | |
| Fusion gene scores | * DoF score | 15 X 17 X 1=255 | 1 X 1 X 1=1 |
| # samples | 17 | 1 | |
| ** MAII score | log2(17/255*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: NPIPB7 [Title/Abstract] AND ATP10B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BX648280 | NPIPB7 | chr16 | 29385597 | + | ATP10B | chr5 | 160100558 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000452313 | ENST00000327245 | NPIPB7 | chr16 | 29385597 | + | ATP10B | chr5 | 160100558 | - |
| intron-intron | ENST00000452313 | ENST00000518411 | NPIPB7 | chr16 | 29385597 | + | ATP10B | chr5 | 160100558 | - |
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FusionProtFeatures for NPIPB7_ATP10B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NPIPB7 | ATP10B |