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Fusion gene ID: 24523 |
FusionGeneSummary for NOA1_ATP10D |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NOA1_ATP10D | Fusion gene ID: 24523 | Hgene | Tgene | Gene symbol | NOA1 | ATP10D | Gene ID | 84273 | 57205 |
| Gene name | nitric oxide associated 1 | ATPase phospholipid transporting 10D (putative) | |
| Synonyms | C4orf14|MTG3|hAtNOS1|hNOA1|mAtNOS1 | ATPVD | |
| Cytomap | 4q12 | 4p12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | nitric oxide-associated protein 1mitochondrial GTPase 3 homolognitric oxide synthase, mitochondrial (putative)putative ortholog of Arabidopsis mitochondrial nitric oxide synthase | probable phospholipid-transporting ATPase VDATPase, class V, type 10DP4-ATPase flippase complex alpha subunit ATP10Dtype IV aminophospholipid transporting ATPase | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q8NC60 | Q9P241 | |
| Ensembl transtripts involved in fusion gene | ENST00000264230, | ENST00000273859, ENST00000504445, ENST00000512393, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 1 X 1 X 1=1 |
| # samples | 3 | 1 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: NOA1 [Title/Abstract] AND ATP10D [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BLCA | TCGA-K4-A83P-01A | NOA1 | chr4 | 57834550 | - | ATP10D | chr4 | 47525029 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000264230 | ENST00000273859 | NOA1 | chr4 | 57834550 | - | ATP10D | chr4 | 47525029 | + |
| Frame-shift | ENST00000264230 | ENST00000504445 | NOA1 | chr4 | 57834550 | - | ATP10D | chr4 | 47525029 | + |
| 5CDS-intron | ENST00000264230 | ENST00000512393 | NOA1 | chr4 | 57834550 | - | ATP10D | chr4 | 47525029 | + |
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FusionProtFeatures for NOA1_ATP10D |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NOA1 | ATP10D |