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Fusion gene ID: 24062

FusionGeneSummary for NEU1_NEU1

Fusion gene summary

Fusion gene information	Fusion gene name: NEU1_NEU1
	Fusion gene ID: 24062
		Hgene	Tgene
	Gene symbol	NEU1	NEU1
	Gene ID	4758	4758
	Gene name	neuraminidase 1	neuraminidase 1
	Synonyms	NANH\|NEU\|SIAL1	NANH\|NEU\|SIAL1
	Cytomap	6p21.33	6p21.33
	Type of gene	protein-coding	protein-coding
	Description	sialidase-1G9 sialidaseN-acetyl-alpha-neuraminidase 1acetylneuraminyl hydrolaseexo-alpha-sialidaselysosomal sialidasesialidase 1 (lysosomal sialidase)	sialidase-1G9 sialidaseN-acetyl-alpha-neuraminidase 1acetylneuraminyl hydrolaseexo-alpha-sialidaselysosomal sialidasesialidase 1 (lysosomal sialidase)
	Modification date	20180523	20180523
	UniProtAcc	Q99519	Q99519
	Ensembl transtripts involved in fusion gene	ENST00000375631, ENST00000423382, ENST00000439648, ENST00000434496, ENST00000422978, ENST00000229725, ENST00000437432, ENST00000411774,	ENST00000375631, ENST00000423382, ENST00000439648, ENST00000434496, ENST00000422978, ENST00000229725, ENST00000437432, ENST00000411774,
Fusion gene scores	* DoF score	2 X 3 X 1=6	2 X 3 X 1=6
	# samples	3	3
	** MAII score	log2(3/6*10)=2.32192809488736	log2(3/6*10)=2.32192809488736
Context	PubMed: NEU1 [Title/Abstract] AND NEU1 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS3.1			AI368907	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
ChiTaRS3.1			BQ301319	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-intron	ENST00000375631	ENST00000375631	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000375631	ENST00000423382	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000375631	ENST00000439648	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000375631	ENST00000434496	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000375631	ENST00000422978	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000375631	ENST00000229725	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000375631	ENST00000437432	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-3UTR	ENST00000375631	ENST00000411774	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000423382	ENST00000375631	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000423382	ENST00000423382	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000423382	ENST00000439648	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000423382	ENST00000434496	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000423382	ENST00000422978	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000423382	ENST00000229725	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000423382	ENST00000437432	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-3UTR	ENST00000423382	ENST00000411774	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000439648	ENST00000375631	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000439648	ENST00000423382	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000439648	ENST00000439648	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000439648	ENST00000434496	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000439648	ENST00000422978	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000439648	ENST00000229725	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000439648	ENST00000437432	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-3UTR	ENST00000439648	ENST00000411774	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000434496	ENST00000375631	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000434496	ENST00000423382	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000434496	ENST00000439648	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000434496	ENST00000434496	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000434496	ENST00000422978	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000434496	ENST00000229725	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000434496	ENST00000437432	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-3UTR	ENST00000434496	ENST00000411774	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000422978	ENST00000375631	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000422978	ENST00000423382	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000422978	ENST00000439648	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000422978	ENST00000434496	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000422978	ENST00000422978	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000422978	ENST00000229725	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000422978	ENST00000437432	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-3UTR	ENST00000422978	ENST00000411774	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000229725	ENST00000375631	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000229725	ENST00000423382	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000229725	ENST00000439648	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000229725	ENST00000434496	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000229725	ENST00000422978	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000229725	ENST00000229725	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000229725	ENST00000437432	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-3UTR	ENST00000229725	ENST00000411774	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000437432	ENST00000375631	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000437432	ENST00000423382	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000437432	ENST00000439648	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000437432	ENST00000434496	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000437432	ENST00000422978	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000437432	ENST00000229725	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000437432	ENST00000437432	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-3UTR	ENST00000437432	ENST00000411774	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000411774	ENST00000375631	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000411774	ENST00000423382	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000411774	ENST00000439648	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000411774	ENST00000434496	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000411774	ENST00000422978	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000411774	ENST00000229725	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000411774	ENST00000437432	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-3UTR	ENST00000411774	ENST00000411774	NEU1	chr6	3160129	-	NEU1	chr6	3159826	+
intron-intron	ENST00000375631	ENST00000375631	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000375631	ENST00000423382	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000375631	ENST00000439648	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000375631	ENST00000434496	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000375631	ENST00000422978	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000375631	ENST00000229725	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000375631	ENST00000437432	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000375631	ENST00000411774	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000423382	ENST00000375631	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000423382	ENST00000423382	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000423382	ENST00000439648	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000423382	ENST00000434496	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000423382	ENST00000422978	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000423382	ENST00000229725	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000423382	ENST00000437432	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000423382	ENST00000411774	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000439648	ENST00000375631	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000439648	ENST00000423382	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000439648	ENST00000439648	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000439648	ENST00000434496	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000439648	ENST00000422978	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000439648	ENST00000229725	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000439648	ENST00000437432	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000439648	ENST00000411774	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000434496	ENST00000375631	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000434496	ENST00000423382	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000434496	ENST00000439648	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000434496	ENST00000434496	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000434496	ENST00000422978	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000434496	ENST00000229725	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000434496	ENST00000437432	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000434496	ENST00000411774	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000422978	ENST00000375631	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000422978	ENST00000423382	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000422978	ENST00000439648	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000422978	ENST00000434496	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000422978	ENST00000422978	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000422978	ENST00000229725	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000422978	ENST00000437432	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000422978	ENST00000411774	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000229725	ENST00000375631	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000229725	ENST00000423382	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000229725	ENST00000439648	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000229725	ENST00000434496	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000229725	ENST00000422978	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000229725	ENST00000229725	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000229725	ENST00000437432	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000229725	ENST00000411774	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000437432	ENST00000375631	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000437432	ENST00000423382	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000437432	ENST00000439648	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000437432	ENST00000434496	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000437432	ENST00000422978	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000437432	ENST00000229725	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000437432	ENST00000437432	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000437432	ENST00000411774	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000411774	ENST00000375631	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000411774	ENST00000423382	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000411774	ENST00000439648	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000411774	ENST00000434496	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000411774	ENST00000422978	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000411774	ENST00000229725	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000411774	ENST00000437432	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-
intron-intron	ENST00000411774	ENST00000411774	NEU1	chr6	3160581	-	NEU1	chr6	3161005	-

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FusionProtFeatures for NEU1_NEU1

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
NEU1 Q99519	NEU1 Q99519

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Fusion gene ID: 24062

FusionGeneSummary for NEU1_NEU1

FusionProtFeatures for NEU1_NEU1