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Fusion gene ID: 2386 |
FusionGeneSummary for ARHGAP19_RRP12 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARHGAP19_RRP12 | Fusion gene ID: 2386 | Hgene | Tgene | Gene symbol | ARHGAP19 | RRP12 | Gene ID | 84986 | 23223 |
| Gene name | Rho GTPase activating protein 19 | ribosomal RNA processing 12 homolog | |
| Synonyms | - | KIAA0690 | |
| Cytomap | 10q24.1 | 10q24.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | rho GTPase-activating protein 19putative RhoGAP proteinrho-type GTPase-activating protein 19 | RRP12-like protein | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q14CB8 | Q5JTH9 | |
| Ensembl transtripts involved in fusion gene | ENST00000355366, ENST00000358531, ENST00000487035, ENST00000371027, | ENST00000479481, ENST00000370992, ENST00000536831, ENST00000315563, ENST00000414986, | |
| Fusion gene scores | * DoF score | 2 X 3 X 3=18 | 4 X 5 X 4=80 |
| # samples | 4 | 5 | |
| ** MAII score | log2(4/18*10)=1.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(5/80*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ARHGAP19 [Title/Abstract] AND RRP12 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LIHC | TCGA-EP-A2KA-01A | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| TCGA | RV | THCA | TCGA-DJ-A3VM-01A | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000355366 | ENST00000479481 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000355366 | ENST00000370992 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000355366 | ENST00000536831 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000355366 | ENST00000315563 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000355366 | ENST00000414986 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000358531 | ENST00000479481 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000358531 | ENST00000370992 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000358531 | ENST00000536831 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000358531 | ENST00000315563 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000358531 | ENST00000414986 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| intron-5UTR | ENST00000487035 | ENST00000479481 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| intron-5UTR | ENST00000487035 | ENST00000370992 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| intron-5UTR | ENST00000487035 | ENST00000536831 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| intron-5UTR | ENST00000487035 | ENST00000315563 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| intron-5UTR | ENST00000487035 | ENST00000414986 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000371027 | ENST00000479481 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000371027 | ENST00000370992 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000371027 | ENST00000536831 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000371027 | ENST00000315563 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-5UTR | ENST00000371027 | ENST00000414986 | ARHGAP19 | chr10 | 99016075 | - | RRP12 | chr10 | 99126889 | - |
| 5CDS-intron | ENST00000355366 | ENST00000479481 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000355366 | ENST00000370992 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000355366 | ENST00000536831 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000355366 | ENST00000315563 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000355366 | ENST00000414986 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000358531 | ENST00000479481 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000358531 | ENST00000370992 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000358531 | ENST00000536831 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000358531 | ENST00000315563 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000358531 | ENST00000414986 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5UTR-intron | ENST00000487035 | ENST00000479481 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5UTR-intron | ENST00000487035 | ENST00000370992 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5UTR-intron | ENST00000487035 | ENST00000536831 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5UTR-intron | ENST00000487035 | ENST00000315563 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5UTR-intron | ENST00000487035 | ENST00000414986 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000371027 | ENST00000479481 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000371027 | ENST00000370992 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000371027 | ENST00000536831 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000371027 | ENST00000315563 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
| 5CDS-intron | ENST00000371027 | ENST00000414986 | ARHGAP19 | chr10 | 98994974 | - | RRP12 | chr10 | 99153517 | - |
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FusionProtFeatures for ARHGAP19_RRP12 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARHGAP19 | RRP12 |