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Fusion gene ID: 23806 |
FusionGeneSummary for NDRG2_RPL38 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NDRG2_RPL38 | Fusion gene ID: 23806 | Hgene | Tgene | Gene symbol | NDRG2 | RPL38 | Gene ID | 57447 | 6169 |
| Gene name | NDRG family member 2 | ribosomal protein L38 | |
| Synonyms | SYLD | L38 | |
| Cytomap | 14q11.2 | 17q25.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein NDRG2N-myc downstream regulator 2N-myc downstream-regulated gene 2 proteinNDR1-related protein NDR2cytoplasmic protein Ndr1syld709613 protein | 60S ribosomal protein L38large ribosomal subunit protein eL38 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9UN36 | P63173 | |
| Ensembl transtripts involved in fusion gene | ENST00000403829, ENST00000298687, ENST00000350792, ENST00000397858, ENST00000554104, ENST00000555158, ENST00000553503, ENST00000397853, ENST00000360463, ENST00000556147, ENST00000397856, ENST00000397855, ENST00000554143, ENST00000397851, ENST00000397847, ENST00000298684, ENST00000397844, ENST00000554277, | ENST00000439590, ENST00000311111, ENST00000584577, ENST00000534490, ENST00000533498, | |
| Fusion gene scores | * DoF score | 11 X 10 X 2=220 | 10 X 10 X 1=100 |
| # samples | 12 | 10 | |
| ** MAII score | log2(12/220*10)=-0.874469117916141 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/100*10)=0 | |
| Context | PubMed: NDRG2 [Title/Abstract] AND RPL38 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | RPL38 | GO:0002181 | cytoplasmic translation | 25957688 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | CK004088 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000403829 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000403829 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000403829 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000403829 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000403829 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000298687 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000298687 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000298687 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000298687 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000298687 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000350792 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000350792 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000350792 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000350792 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000350792 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397858 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397858 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397858 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397858 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397858 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554104 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554104 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554104 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554104 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554104 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000555158 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000555158 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000555158 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000555158 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000555158 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000553503 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000553503 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000553503 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000553503 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000553503 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397853 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397853 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397853 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397853 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397853 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000360463 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000360463 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000360463 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000360463 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000360463 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000556147 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000556147 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000556147 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000556147 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000556147 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397856 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397856 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397856 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397856 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397856 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397855 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397855 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397855 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397855 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397855 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554143 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554143 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554143 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554143 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554143 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397851 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397851 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397851 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397851 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397851 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397847 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397847 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397847 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397847 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397847 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000298684 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000298684 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000298684 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000298684 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000298684 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397844 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397844 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397844 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397844 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000397844 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554277 | ENST00000439590 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554277 | ENST00000311111 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554277 | ENST00000584577 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554277 | ENST00000534490 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
| intron-3CDS | ENST00000554277 | ENST00000533498 | NDRG2 | chr14 | 21486161 | - | RPL38 | chr17 | 72200288 | + |
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FusionProtFeatures for NDRG2_RPL38 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NDRG2 | RPL38 |