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Fusion gene ID: 23749 |
FusionGeneSummary for NCS1_NCS1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NCS1_NCS1 | Fusion gene ID: 23749 | Hgene | Tgene | Gene symbol | NCS1 | NCS1 | Gene ID | 23413 | 23413 |
| Gene name | neuronal calcium sensor 1 | neuronal calcium sensor 1 | |
| Synonyms | FLUP|FREQ | FLUP|FREQ | |
| Cytomap | 9q34.11 | 9q34.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | neuronal calcium sensor 1frequenin homologfrequenin-like proteinfrequenin-like ubiquitous protein | neuronal calcium sensor 1frequenin homologfrequenin-like proteinfrequenin-like ubiquitous protein | |
| Modification date | 20180522 | 20180522 | |
| UniProtAcc | P62166 | P62166 | |
| Ensembl transtripts involved in fusion gene | ENST00000372398, ENST00000493042, ENST00000458469, | ENST00000372398, ENST00000493042, ENST00000458469, | |
| Fusion gene scores | * DoF score | 3 X 3 X 3=27 | 3 X 3 X 3=27 |
| # samples | 4 | 4 | |
| ** MAII score | log2(4/27*10)=0.567040592723894 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/27*10)=0.567040592723894 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: NCS1 [Title/Abstract] AND NCS1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BG472770 | NCS1 | chr9 | 132998320 | + | NCS1 | chr9 | 132997416 | + | ||
| ChiTaRS3.1 | BE256096 | NCS1 | chr9 | 132998320 | + | NCS1 | chr9 | 132997416 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3UTR | ENST00000372398 | ENST00000372398 | NCS1 | chr9 | 132998320 | + | NCS1 | chr9 | 132997416 | + |
| 3UTR-intron | ENST00000372398 | ENST00000493042 | NCS1 | chr9 | 132998320 | + | NCS1 | chr9 | 132997416 | + |
| 3UTR-3UTR | ENST00000372398 | ENST00000458469 | NCS1 | chr9 | 132998320 | + | NCS1 | chr9 | 132997416 | + |
| intron-3UTR | ENST00000493042 | ENST00000372398 | NCS1 | chr9 | 132998320 | + | NCS1 | chr9 | 132997416 | + |
| intron-intron | ENST00000493042 | ENST00000493042 | NCS1 | chr9 | 132998320 | + | NCS1 | chr9 | 132997416 | + |
| intron-3UTR | ENST00000493042 | ENST00000458469 | NCS1 | chr9 | 132998320 | + | NCS1 | chr9 | 132997416 | + |
| 3UTR-3UTR | ENST00000458469 | ENST00000372398 | NCS1 | chr9 | 132998320 | + | NCS1 | chr9 | 132997416 | + |
| 3UTR-intron | ENST00000458469 | ENST00000493042 | NCS1 | chr9 | 132998320 | + | NCS1 | chr9 | 132997416 | + |
| 3UTR-3UTR | ENST00000458469 | ENST00000458469 | NCS1 | chr9 | 132998320 | + | NCS1 | chr9 | 132997416 | + |
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FusionProtFeatures for NCS1_NCS1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NCS1 | NCS1 |