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Fusion gene ID: 23575 |
FusionGeneSummary for NCDN_TMSB10 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NCDN_TMSB10 | Fusion gene ID: 23575 | Hgene | Tgene | Gene symbol | NCDN | TMSB10 | Gene ID | 23154 | 9168 |
| Gene name | neurochondrin | thymosin beta 10 | |
| Synonyms | - | MIG12|TB10 | |
| Cytomap | 1p34.3 | 2p11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | neurochondrin | thymosin beta-10migration-inducing gene 12migration-inducing protein 12 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q9UBB6 | P63313 | |
| Ensembl transtripts involved in fusion gene | ENST00000373253, ENST00000356090, ENST00000373243, ENST00000459931, | ENST00000233143, | |
| Fusion gene scores | * DoF score | 3 X 3 X 1=9 | 9 X 9 X 1=81 |
| # samples | 3 | 11 | |
| ** MAII score | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(11/81*10)=0.441509710640035 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: NCDN [Title/Abstract] AND TMSB10 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | M79087 | NCDN | chr1 | 36031945 | - | TMSB10 | chr2 | 85132788 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-5UTR | ENST00000373253 | ENST00000233143 | NCDN | chr1 | 36031945 | - | TMSB10 | chr2 | 85132788 | + |
| 3UTR-5UTR | ENST00000356090 | ENST00000233143 | NCDN | chr1 | 36031945 | - | TMSB10 | chr2 | 85132788 | + |
| 3UTR-5UTR | ENST00000373243 | ENST00000233143 | NCDN | chr1 | 36031945 | - | TMSB10 | chr2 | 85132788 | + |
| intron-5UTR | ENST00000459931 | ENST00000233143 | NCDN | chr1 | 36031945 | - | TMSB10 | chr2 | 85132788 | + |
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FusionProtFeatures for NCDN_TMSB10 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NCDN | TMSB10 |