|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 23549 |
FusionGeneSummary for NCAM2_CYP4F29P |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NCAM2_CYP4F29P | Fusion gene ID: 23549 | Hgene | Tgene | Gene symbol | NCAM2 | CYP4F29P | Gene ID | 4685 | 54055 |
| Gene name | neural cell adhesion molecule 2 | cytochrome P450 family 4 subfamily F member 29, pseudogene | |
| Synonyms | NCAM21 | 4F-se4[6:7:8]|C21orf15|CYP4F-se4[6:7:8]|CYP4F3LP | |
| Cytomap | 21q21.1 | 21q11.2 | |
| Type of gene | protein-coding | pseudo | |
| Description | neural cell adhesion molecule 2N-CAM-2NCAM-2 | cytochrome P450 pseudogenecytochrome P450, family 4, subfamily F, polypeptide 29, pseudogenecytochrome P450, family 4, subfamily F, polypeptide 3-like pseudogenecytochrome P450, subfamily IVF, polypeptide 3-like pseudogene | |
| Modification date | 20180523 | 20180329 | |
| UniProtAcc | O15394 | ||
| Ensembl transtripts involved in fusion gene | ENST00000400546, ENST00000284894, ENST00000535285, ENST00000486367, | ENST00000428301, | |
| Fusion gene scores | * DoF score | 9 X 4 X 5=180 | 1 X 1 X 1=1 |
| # samples | 9 | 1 | |
| ** MAII score | log2(9/180*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: NCAM2 [Title/Abstract] AND CYP4F29P [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LGG | TCGA-E1-5304-01A | NCAM2 | chr21 | 22370936 | + | CYP4F29P | chr21 | 15218462 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000400546 | ENST00000428301 | NCAM2 | chr21 | 22370936 | + | CYP4F29P | chr21 | 15218462 | - |
| 5CDS-5UTR | ENST00000284894 | ENST00000428301 | NCAM2 | chr21 | 22370936 | + | CYP4F29P | chr21 | 15218462 | - |
| intron-5UTR | ENST00000535285 | ENST00000428301 | NCAM2 | chr21 | 22370936 | + | CYP4F29P | chr21 | 15218462 | - |
| intron-5UTR | ENST00000486367 | ENST00000428301 | NCAM2 | chr21 | 22370936 | + | CYP4F29P | chr21 | 15218462 | - |
Top |
FusionProtFeatures for NCAM2_CYP4F29P |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NCAM2 | CYP4F29P |