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Fusion gene ID: 23491 |
FusionGeneSummary for NBAS_THADA |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NBAS_THADA | Fusion gene ID: 23491 | Hgene | Tgene | Gene symbol | NBAS | THADA | Gene ID | 51594 | 63892 |
| Gene name | neuroblastoma amplified sequence | THADA, armadillo repeat containing | |
| Synonyms | ILFS2|NAG|SOPH | ARMC13|GITA | |
| Cytomap | 2p24.3 | 2p21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | neuroblastoma-amplified sequenceNAG/BC035112 fusionNAG/FAM49A fusionneuroblastoma-amplified gene protein | thyroid adenoma-associated proteindeath receptor-interacting proteingene inducing thyroid adenomas protein | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | A2RRP1 | Q6YHU6 | |
| Ensembl transtripts involved in fusion gene | ENST00000441750, ENST00000281513, | ENST00000330266, ENST00000405975, ENST00000415080, ENST00000405006, ENST00000485353, ENST00000402360, ENST00000404790, ENST00000403856, | |
| Fusion gene scores | * DoF score | 11 X 10 X 7=770 | 9 X 9 X 7=567 |
| # samples | 12 | 10 | |
| ** MAII score | log2(12/770*10)=-2.68182403997375 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/567*10)=-2.5033487351675 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: NBAS [Title/Abstract] AND THADA [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-AO-A0J4-01A | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000441750 | ENST00000330266 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-5UTR | ENST00000441750 | ENST00000405975 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-5UTR | ENST00000441750 | ENST00000415080 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-5UTR | ENST00000441750 | ENST00000405006 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-intron | ENST00000441750 | ENST00000485353 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-intron | ENST00000441750 | ENST00000402360 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-5UTR | ENST00000441750 | ENST00000404790 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-5UTR | ENST00000441750 | ENST00000403856 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-intron | ENST00000281513 | ENST00000330266 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-5UTR | ENST00000281513 | ENST00000405975 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-5UTR | ENST00000281513 | ENST00000415080 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-5UTR | ENST00000281513 | ENST00000405006 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-intron | ENST00000281513 | ENST00000485353 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-intron | ENST00000281513 | ENST00000402360 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-5UTR | ENST00000281513 | ENST00000404790 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
| 5CDS-5UTR | ENST00000281513 | ENST00000403856 | NBAS | chr2 | 15467874 | - | THADA | chr2 | 43819555 | - |
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FusionProtFeatures for NBAS_THADA |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NBAS | THADA |