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Fusion gene ID: 23391 |
FusionGeneSummary for NAP1L1_WHSC1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: NAP1L1_WHSC1 | Fusion gene ID: 23391 | Hgene | Tgene | Gene symbol | NAP1L1 | WHSC1 | Gene ID | 4673 | 7468 |
| Gene name | nucleosome assembly protein 1 like 1 | nuclear receptor binding SET domain protein 2 | |
| Synonyms | NAP1|NAP1L|NRP | KMT3F|KMT3G|MMSET|REIIBP|TRX5|WHS|WHSC1 | |
| Cytomap | 12q21.2 | 4p16.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | nucleosome assembly protein 1-like 1HSP22-like protein interacting proteinNAP-1-related protein | histone-lysine N-methyltransferase NSD2IL5 promoter REII region-binding proteinWolf-Hirschhorn syndrome candidate 1multiple myeloma SET domain containing protein type IIInuclear SET domain-containing protein 2probable histone-lysine N-methyltransfera | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | P55209 | ||
| Ensembl transtripts involved in fusion gene | ENST00000261182, ENST00000393263, ENST00000431879, ENST00000547773, ENST00000544816, ENST00000542344, ENST00000535020, ENST00000549596, ENST00000547993, ENST00000552342, ENST00000548044, | ENST00000508803, ENST00000382892, ENST00000382891, ENST00000382895, ENST00000482415, ENST00000382888, ENST00000514045, ENST00000436793, ENST00000420906, ENST00000503128, ENST00000398261, | |
| Fusion gene scores | * DoF score | 10 X 7 X 4=280 | 5 X 5 X 1=25 |
| # samples | 12 | 6 | |
| ** MAII score | log2(12/280*10)=-1.22239242133645 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/25*10)=1.26303440583379 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: NAP1L1 [Title/Abstract] AND WHSC1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DA779343 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000261182 | ENST00000508803 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000261182 | ENST00000382892 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000261182 | ENST00000382891 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000261182 | ENST00000382895 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000261182 | ENST00000482415 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000261182 | ENST00000382888 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000261182 | ENST00000514045 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000261182 | ENST00000436793 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000261182 | ENST00000420906 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000261182 | ENST00000503128 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000261182 | ENST00000398261 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000393263 | ENST00000508803 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000393263 | ENST00000382892 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000393263 | ENST00000382891 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000393263 | ENST00000382895 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000393263 | ENST00000482415 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000393263 | ENST00000382888 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000393263 | ENST00000514045 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000393263 | ENST00000436793 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000393263 | ENST00000420906 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000393263 | ENST00000503128 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000393263 | ENST00000398261 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000431879 | ENST00000508803 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000431879 | ENST00000382892 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000431879 | ENST00000382891 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000431879 | ENST00000382895 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-intron | ENST00000431879 | ENST00000482415 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-intron | ENST00000431879 | ENST00000382888 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000431879 | ENST00000514045 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000431879 | ENST00000436793 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000431879 | ENST00000420906 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000431879 | ENST00000503128 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000431879 | ENST00000398261 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000547773 | ENST00000508803 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000547773 | ENST00000382892 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000547773 | ENST00000382891 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000547773 | ENST00000382895 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000547773 | ENST00000482415 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000547773 | ENST00000382888 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000547773 | ENST00000514045 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000547773 | ENST00000436793 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000547773 | ENST00000420906 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000547773 | ENST00000503128 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000547773 | ENST00000398261 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000544816 | ENST00000508803 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000544816 | ENST00000382892 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000544816 | ENST00000382891 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000544816 | ENST00000382895 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-intron | ENST00000544816 | ENST00000482415 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-intron | ENST00000544816 | ENST00000382888 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000544816 | ENST00000514045 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000544816 | ENST00000436793 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000544816 | ENST00000420906 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000544816 | ENST00000503128 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000544816 | ENST00000398261 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5UTR-5UTR | ENST00000542344 | ENST00000508803 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5UTR-5UTR | ENST00000542344 | ENST00000382892 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5UTR-5UTR | ENST00000542344 | ENST00000382891 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5UTR-5UTR | ENST00000542344 | ENST00000382895 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5UTR-intron | ENST00000542344 | ENST00000482415 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5UTR-intron | ENST00000542344 | ENST00000382888 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5UTR-5UTR | ENST00000542344 | ENST00000514045 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5UTR-5UTR | ENST00000542344 | ENST00000436793 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5UTR-5UTR | ENST00000542344 | ENST00000420906 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5UTR-5UTR | ENST00000542344 | ENST00000503128 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5UTR-5UTR | ENST00000542344 | ENST00000398261 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000535020 | ENST00000508803 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000535020 | ENST00000382892 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000535020 | ENST00000382891 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000535020 | ENST00000382895 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000535020 | ENST00000482415 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000535020 | ENST00000382888 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000535020 | ENST00000514045 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000535020 | ENST00000436793 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000535020 | ENST00000420906 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000535020 | ENST00000503128 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000535020 | ENST00000398261 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000549596 | ENST00000508803 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000549596 | ENST00000382892 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000549596 | ENST00000382891 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000549596 | ENST00000382895 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000549596 | ENST00000482415 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000549596 | ENST00000382888 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000549596 | ENST00000514045 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000549596 | ENST00000436793 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000549596 | ENST00000420906 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000549596 | ENST00000503128 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000549596 | ENST00000398261 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000547993 | ENST00000508803 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000547993 | ENST00000382892 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000547993 | ENST00000382891 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000547993 | ENST00000382895 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-intron | ENST00000547993 | ENST00000482415 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-intron | ENST00000547993 | ENST00000382888 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000547993 | ENST00000514045 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000547993 | ENST00000436793 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000547993 | ENST00000420906 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000547993 | ENST00000503128 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000547993 | ENST00000398261 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000552342 | ENST00000508803 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000552342 | ENST00000382892 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000552342 | ENST00000382891 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000552342 | ENST00000382895 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000552342 | ENST00000482415 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-intron | ENST00000552342 | ENST00000382888 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000552342 | ENST00000514045 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000552342 | ENST00000436793 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000552342 | ENST00000420906 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000552342 | ENST00000503128 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| 5CDS-5UTR | ENST00000552342 | ENST00000398261 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000548044 | ENST00000508803 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000548044 | ENST00000382892 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000548044 | ENST00000382891 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000548044 | ENST00000382895 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-intron | ENST00000548044 | ENST00000482415 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-intron | ENST00000548044 | ENST00000382888 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000548044 | ENST00000514045 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000548044 | ENST00000436793 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000548044 | ENST00000420906 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000548044 | ENST00000503128 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
| intron-5UTR | ENST00000548044 | ENST00000398261 | NAP1L1 | chr12 | 76467983 | - | WHSC1 | chr4 | 1902353 | + |
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FusionProtFeatures for NAP1L1_WHSC1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| NAP1L1 | WHSC1 |