|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 2334 |
FusionGeneSummary for ARFGAP3_ARFGAP3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARFGAP3_ARFGAP3 | Fusion gene ID: 2334 | Hgene | Tgene | Gene symbol | ARFGAP3 | ARFGAP3 | Gene ID | 26286 | 26286 |
| Gene name | ADP ribosylation factor GTPase activating protein 3 | ADP ribosylation factor GTPase activating protein 3 | |
| Synonyms | ARFGAP1 | ARFGAP1 | |
| Cytomap | 22q13.2 | 22q13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ADP-ribosylation factor GTPase-activating protein 3ADP-ribosylation factor GTPase activating protein 1ARF GAP 3 | ADP-ribosylation factor GTPase-activating protein 3ADP-ribosylation factor GTPase activating protein 1ARF GAP 3 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9NP61 | Q9NP61 | |
| Ensembl transtripts involved in fusion gene | ENST00000263245, ENST00000429508, ENST00000437119, | ENST00000263245, ENST00000429508, ENST00000437119, | |
| Fusion gene scores | * DoF score | 4 X 3 X 4=48 | 5 X 5 X 4=100 |
| # samples | 4 | 7 | |
| ** MAII score | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/100*10)=-0.514573172829758 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ARFGAP3 [Title/Abstract] AND ARFGAP3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AU185860 | ARFGAP3 | chr22 | 43203143 | - | ARFGAP3 | chr22 | 43219710 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000263245 | ENST00000263245 | ARFGAP3 | chr22 | 43203143 | - | ARFGAP3 | chr22 | 43219710 | - |
| intron-3CDS | ENST00000263245 | ENST00000429508 | ARFGAP3 | chr22 | 43203143 | - | ARFGAP3 | chr22 | 43219710 | - |
| intron-3CDS | ENST00000263245 | ENST00000437119 | ARFGAP3 | chr22 | 43203143 | - | ARFGAP3 | chr22 | 43219710 | - |
| intron-3CDS | ENST00000429508 | ENST00000263245 | ARFGAP3 | chr22 | 43203143 | - | ARFGAP3 | chr22 | 43219710 | - |
| intron-3CDS | ENST00000429508 | ENST00000429508 | ARFGAP3 | chr22 | 43203143 | - | ARFGAP3 | chr22 | 43219710 | - |
| intron-3CDS | ENST00000429508 | ENST00000437119 | ARFGAP3 | chr22 | 43203143 | - | ARFGAP3 | chr22 | 43219710 | - |
| intron-3CDS | ENST00000437119 | ENST00000263245 | ARFGAP3 | chr22 | 43203143 | - | ARFGAP3 | chr22 | 43219710 | - |
| intron-3CDS | ENST00000437119 | ENST00000429508 | ARFGAP3 | chr22 | 43203143 | - | ARFGAP3 | chr22 | 43219710 | - |
| intron-3CDS | ENST00000437119 | ENST00000437119 | ARFGAP3 | chr22 | 43203143 | - | ARFGAP3 | chr22 | 43219710 | - |
Top |
FusionProtFeatures for ARFGAP3_ARFGAP3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARFGAP3 | ARFGAP3 |