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Fusion gene ID: 2329 |
FusionGeneSummary for ARFGAP2_ARFGAP2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ARFGAP2_ARFGAP2 | Fusion gene ID: 2329 | Hgene | Tgene | Gene symbol | ARFGAP2 | ARFGAP2 | Gene ID | 84364 | 84364 |
| Gene name | ADP ribosylation factor GTPase activating protein 2 | ADP ribosylation factor GTPase activating protein 2 | |
| Synonyms | IRZ|NBLA10535|ZFP289|ZNF289 | IRZ|NBLA10535|ZFP289|ZNF289 | |
| Cytomap | 11p11.2 | 11p11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ADP-ribosylation factor GTPase-activating protein 2GTPase-activating protein ZNF289zinc finger protein 289, ID1 regulated | ADP-ribosylation factor GTPase-activating protein 2GTPase-activating protein ZNF289zinc finger protein 289, ID1 regulated | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q8N6H7 | Q8N6H7 | |
| Ensembl transtripts involved in fusion gene | ENST00000426335, ENST00000524782, ENST00000395449, ENST00000319543, ENST00000419701, | ENST00000426335, ENST00000524782, ENST00000395449, ENST00000319543, ENST00000419701, | |
| Fusion gene scores | * DoF score | 5 X 5 X 4=100 | 2 X 2 X 2=8 |
| # samples | 5 | 2 | |
| ** MAII score | log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: ARFGAP2 [Title/Abstract] AND ARFGAP2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BP194100 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000426335 | ENST00000426335 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-3CDS | ENST00000426335 | ENST00000524782 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000426335 | ENST00000395449 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000426335 | ENST00000319543 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000426335 | ENST00000419701 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-3CDS | ENST00000524782 | ENST00000426335 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-3CDS | ENST00000524782 | ENST00000524782 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000524782 | ENST00000395449 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000524782 | ENST00000319543 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000524782 | ENST00000419701 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-3CDS | ENST00000395449 | ENST00000426335 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-3CDS | ENST00000395449 | ENST00000524782 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000395449 | ENST00000395449 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000395449 | ENST00000319543 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000395449 | ENST00000419701 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-3CDS | ENST00000319543 | ENST00000426335 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-3CDS | ENST00000319543 | ENST00000524782 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000319543 | ENST00000395449 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000319543 | ENST00000319543 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000319543 | ENST00000419701 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-3CDS | ENST00000419701 | ENST00000426335 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-3CDS | ENST00000419701 | ENST00000524782 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000419701 | ENST00000395449 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000419701 | ENST00000319543 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
| intron-5UTR | ENST00000419701 | ENST00000419701 | ARFGAP2 | chr11 | 47186181 | - | ARFGAP2 | chr11 | 47188385 | - |
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FusionProtFeatures for ARFGAP2_ARFGAP2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ARFGAP2 | ARFGAP2 |