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Fusion gene ID: 22843 |
FusionGeneSummary for MTSS1_TATDN1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MTSS1_TATDN1 | Fusion gene ID: 22843 | Hgene | Tgene | Gene symbol | MTSS1 | TATDN1 | Gene ID | 9788 | 83940 |
| Gene name | MTSS1, I-BAR domain containing | TatD DNase domain containing 1 | |
| Synonyms | MIM|MIMA|MIMB | CDA11 | |
| Cytomap | 8q24.13 | 8q24.13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | metastasis suppressor protein 1metastasis suppressor 1metastasis suppressor YGL-1missing in metastasis protein | putative deoxyribonuclease TATDN1hepatocarcinoma high expression protein | |
| Modification date | 20180519 | 20180526 | |
| UniProtAcc | O43312 | Q6P1N9 | |
| Ensembl transtripts involved in fusion gene | ENST00000378017, ENST00000518547, ENST00000354184, ENST00000395508, ENST00000325064, ENST00000431961, ENST00000523587, ENST00000524090, | ENST00000276692, ENST00000519548, ENST00000517678, ENST00000521546, ENST00000605953, | |
| Fusion gene scores | * DoF score | 8 X 5 X 6=240 | 4 X 2 X 3=24 |
| # samples | 8 | 4 | |
| ** MAII score | log2(8/240*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/24*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: MTSS1 [Title/Abstract] AND TATDN1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BLCA | TCGA-FD-A3N5-01A | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000378017 | ENST00000276692 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| In-frame | ENST00000378017 | ENST00000519548 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5CDS-intron | ENST00000378017 | ENST00000517678 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5CDS-intron | ENST00000378017 | ENST00000521546 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5CDS-intron | ENST00000378017 | ENST00000605953 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| Frame-shift | ENST00000518547 | ENST00000276692 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| In-frame | ENST00000518547 | ENST00000519548 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5CDS-intron | ENST00000518547 | ENST00000517678 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5CDS-intron | ENST00000518547 | ENST00000521546 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5CDS-intron | ENST00000518547 | ENST00000605953 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5UTR-3CDS | ENST00000354184 | ENST00000276692 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5UTR-3CDS | ENST00000354184 | ENST00000519548 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5UTR-intron | ENST00000354184 | ENST00000517678 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5UTR-intron | ENST00000354184 | ENST00000521546 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5UTR-intron | ENST00000354184 | ENST00000605953 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-3CDS | ENST00000395508 | ENST00000276692 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-3CDS | ENST00000395508 | ENST00000519548 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000395508 | ENST00000517678 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000395508 | ENST00000521546 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000395508 | ENST00000605953 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| Frame-shift | ENST00000325064 | ENST00000276692 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| In-frame | ENST00000325064 | ENST00000519548 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5CDS-intron | ENST00000325064 | ENST00000517678 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5CDS-intron | ENST00000325064 | ENST00000521546 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| 5CDS-intron | ENST00000325064 | ENST00000605953 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-3CDS | ENST00000431961 | ENST00000276692 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-3CDS | ENST00000431961 | ENST00000519548 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000431961 | ENST00000517678 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000431961 | ENST00000521546 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000431961 | ENST00000605953 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-3CDS | ENST00000523587 | ENST00000276692 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-3CDS | ENST00000523587 | ENST00000519548 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000523587 | ENST00000517678 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000523587 | ENST00000521546 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000523587 | ENST00000605953 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-3CDS | ENST00000524090 | ENST00000276692 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-3CDS | ENST00000524090 | ENST00000519548 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000524090 | ENST00000517678 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000524090 | ENST00000521546 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
| intron-intron | ENST00000524090 | ENST00000605953 | MTSS1 | chr8 | 125711767 | - | TATDN1 | chr8 | 125500937 | - |
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FusionProtFeatures for MTSS1_TATDN1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MTSS1 | TATDN1 |