|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 22408 |
FusionGeneSummary for MPZL1_MPZL1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MPZL1_MPZL1 | Fusion gene ID: 22408 | Hgene | Tgene | Gene symbol | MPZL1 | MPZL1 | Gene ID | 9019 | 9019 |
| Gene name | myelin protein zero like 1 | myelin protein zero like 1 | |
| Synonyms | MPZL1b|PZR|PZR1b|PZRa|PZRb | MPZL1b|PZR|PZR1b|PZRa|PZRb | |
| Cytomap | 1q24.2 | 1q24.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | myelin protein zero-like protein 1immunoglobulin family transmembrane proteinprotein zero related | myelin protein zero-like protein 1immunoglobulin family transmembrane proteinprotein zero related | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | O95297 | O95297 | |
| Ensembl transtripts involved in fusion gene | ENST00000359523, ENST00000392121, ENST00000474859, ENST00000403379, | ENST00000359523, ENST00000392121, ENST00000474859, ENST00000403379, | |
| Fusion gene scores | * DoF score | 6 X 4 X 5=120 | 2 X 2 X 3=12 |
| # samples | 6 | 5 | |
| ** MAII score | log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(5/12*10)=2.05889368905357 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: MPZL1 [Title/Abstract] AND MPZL1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | CA420334 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3UTR | ENST00000359523 | ENST00000359523 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| 3UTR-3UTR | ENST00000359523 | ENST00000392121 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| 3UTR-intron | ENST00000359523 | ENST00000474859 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| 3UTR-intron | ENST00000359523 | ENST00000403379 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| 3UTR-3UTR | ENST00000392121 | ENST00000359523 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| 3UTR-3UTR | ENST00000392121 | ENST00000392121 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| 3UTR-intron | ENST00000392121 | ENST00000474859 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| 3UTR-intron | ENST00000392121 | ENST00000403379 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| intron-3UTR | ENST00000474859 | ENST00000359523 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| intron-3UTR | ENST00000474859 | ENST00000392121 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| intron-intron | ENST00000474859 | ENST00000474859 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| intron-intron | ENST00000474859 | ENST00000403379 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| intron-3UTR | ENST00000403379 | ENST00000359523 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| intron-3UTR | ENST00000403379 | ENST00000392121 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| intron-intron | ENST00000403379 | ENST00000474859 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
| intron-intron | ENST00000403379 | ENST00000403379 | MPZL1 | chr1 | 167759273 | - | MPZL1 | chr1 | 167759691 | - |
Top |
FusionProtFeatures for MPZL1_MPZL1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MPZL1 | MPZL1 |