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Fusion gene ID: 22028 |
FusionGeneSummary for MIR548G_TNS1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MIR548G_TNS1 | Fusion gene ID: 22028 | Hgene | Tgene | Gene symbol | MIR548G | TNS1 | Gene ID | 100313938 | 7145 |
| Gene name | microRNA 548g | tensin 1 | |
| Synonyms | MIRN548G|hsa-mir-548g | MST091|MST122|MST127|MSTP091|MSTP122|MSTP127|MXRA6|PPP1R155|TNS | |
| Cytomap | 4q31.22 | 2q35 | |
| Type of gene | ncRNA | protein-coding | |
| Description | - | tensin-1Matrix-remodelling-associated protein 6matrix-remodelling associated 6protein phosphatase 1, regulatory subunit 155 | |
| Modification date | 20180329 | 20180519 | |
| UniProtAcc | Q9HBL0 | ||
| Ensembl transtripts involved in fusion gene | ENST00000408442, | ENST00000171887, ENST00000419504, ENST00000430930, ENST00000310858, ENST00000480665, | |
| Fusion gene scores | * DoF score | 3 X 4 X 1=12 | 6 X 6 X 2=72 |
| # samples | 4 | 6 | |
| ** MAII score | log2(4/12*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(6/72*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MIR548G [Title/Abstract] AND TNS1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | D79968 | MIR548G | chr3 | 99515019 | - | TNS1 | chr2 | 218664582 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3UTR | ENST00000408442 | ENST00000171887 | MIR548G | chr3 | 99515019 | - | TNS1 | chr2 | 218664582 | - |
| intron-intron | ENST00000408442 | ENST00000419504 | MIR548G | chr3 | 99515019 | - | TNS1 | chr2 | 218664582 | - |
| intron-intron | ENST00000408442 | ENST00000430930 | MIR548G | chr3 | 99515019 | - | TNS1 | chr2 | 218664582 | - |
| intron-intron | ENST00000408442 | ENST00000310858 | MIR548G | chr3 | 99515019 | - | TNS1 | chr2 | 218664582 | - |
| intron-intron | ENST00000408442 | ENST00000480665 | MIR548G | chr3 | 99515019 | - | TNS1 | chr2 | 218664582 | - |
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FusionProtFeatures for MIR548G_TNS1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MIR548G | TNS1 |