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Fusion gene ID: 21798 |
FusionGeneSummary for MGAT4C_PPFIA2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MGAT4C_PPFIA2 | Fusion gene ID: 21798 | Hgene | Tgene | Gene symbol | MGAT4C | PPFIA2 | Gene ID | 25834 | 8499 |
| Gene name | MGAT4 family member C | PTPRF interacting protein alpha 2 | |
| Synonyms | GNTIVH|HGNT-IV-H | - | |
| Cytomap | 12q21.31-q21.32 | 12q21.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase CN-acetylglucosaminyltransferase IV homologN-acetylglucosaminyltransferase IVcN-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IVcUDP-N-acetylglucosamine: al | liprin-alpha-2protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 | |
| Modification date | 20180522 | 20180522 | |
| UniProtAcc | Q9UBM8 | O75334 | |
| Ensembl transtripts involved in fusion gene | ENST00000549405, ENST00000393205, ENST00000332156, ENST00000604798, ENST00000552808, ENST00000548651, ENST00000552435, ENST00000602941, | ENST00000549396, ENST00000550584, ENST00000549325, ENST00000545296, ENST00000550359, ENST00000407050, ENST00000333447, ENST00000548586, ENST00000443686, ENST00000552948, ENST00000541570, ENST00000541017, | |
| Fusion gene scores | * DoF score | 6 X 5 X 3=90 | 10 X 5 X 3=150 |
| # samples | 4 | 9 | |
| ** MAII score | log2(4/90*10)=-1.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(9/150*10)=-0.736965594166206 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MGAT4C [Title/Abstract] AND PPFIA2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-3B-A9HS-01A | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000549405 | ENST00000549396 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-3CDS | ENST00000549405 | ENST00000550584 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-3CDS | ENST00000549405 | ENST00000549325 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000549405 | ENST00000545296 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000549405 | ENST00000550359 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000549405 | ENST00000407050 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000549405 | ENST00000333447 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000549405 | ENST00000548586 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000549405 | ENST00000443686 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000549405 | ENST00000552948 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000549405 | ENST00000541570 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000549405 | ENST00000541017 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000393205 | ENST00000549396 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000393205 | ENST00000550584 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000393205 | ENST00000549325 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000393205 | ENST00000545296 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000393205 | ENST00000550359 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000393205 | ENST00000407050 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000393205 | ENST00000333447 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000393205 | ENST00000548586 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000393205 | ENST00000443686 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000393205 | ENST00000552948 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000393205 | ENST00000541570 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000393205 | ENST00000541017 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000332156 | ENST00000549396 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000332156 | ENST00000550584 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000332156 | ENST00000549325 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000332156 | ENST00000545296 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000332156 | ENST00000550359 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000332156 | ENST00000407050 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000332156 | ENST00000333447 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000332156 | ENST00000548586 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000332156 | ENST00000443686 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000332156 | ENST00000552948 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000332156 | ENST00000541570 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000332156 | ENST00000541017 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000604798 | ENST00000549396 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000604798 | ENST00000550584 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000604798 | ENST00000549325 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000604798 | ENST00000545296 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000604798 | ENST00000550359 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000604798 | ENST00000407050 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000604798 | ENST00000333447 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000604798 | ENST00000548586 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000604798 | ENST00000443686 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000604798 | ENST00000552948 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000604798 | ENST00000541570 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000604798 | ENST00000541017 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000552808 | ENST00000549396 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000552808 | ENST00000550584 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000552808 | ENST00000549325 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552808 | ENST00000545296 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552808 | ENST00000550359 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552808 | ENST00000407050 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552808 | ENST00000333447 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552808 | ENST00000548586 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552808 | ENST00000443686 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552808 | ENST00000552948 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552808 | ENST00000541570 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552808 | ENST00000541017 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000548651 | ENST00000549396 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000548651 | ENST00000550584 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000548651 | ENST00000549325 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000548651 | ENST00000545296 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000548651 | ENST00000550359 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000548651 | ENST00000407050 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000548651 | ENST00000333447 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000548651 | ENST00000548586 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000548651 | ENST00000443686 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000548651 | ENST00000552948 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000548651 | ENST00000541570 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000548651 | ENST00000541017 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000552435 | ENST00000549396 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000552435 | ENST00000550584 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-3CDS | ENST00000552435 | ENST00000549325 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552435 | ENST00000545296 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552435 | ENST00000550359 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552435 | ENST00000407050 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552435 | ENST00000333447 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552435 | ENST00000548586 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552435 | ENST00000443686 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552435 | ENST00000552948 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552435 | ENST00000541570 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| intron-intron | ENST00000552435 | ENST00000541017 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-3CDS | ENST00000602941 | ENST00000549396 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-3CDS | ENST00000602941 | ENST00000550584 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-3CDS | ENST00000602941 | ENST00000549325 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000602941 | ENST00000545296 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000602941 | ENST00000550359 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000602941 | ENST00000407050 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000602941 | ENST00000333447 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000602941 | ENST00000548586 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000602941 | ENST00000443686 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000602941 | ENST00000552948 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000602941 | ENST00000541570 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
| 5UTR-intron | ENST00000602941 | ENST00000541017 | MGAT4C | chr12 | 86727843 | - | PPFIA2 | chr12 | 81657169 | - |
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FusionProtFeatures for MGAT4C_PPFIA2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MGAT4C | PPFIA2 |