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Fusion gene ID: 20782 |
FusionGeneSummary for MAP1B_MAP1B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MAP1B_MAP1B | Fusion gene ID: 20782 | Hgene | Tgene | Gene symbol | MAP1B | MAP1B | Gene ID | 4131 | 4131 |
| Gene name | microtubule associated protein 1B | microtubule associated protein 1B | |
| Synonyms | FUTSCH|MAP5|PPP1R102 | FUTSCH|MAP5|PPP1R102 | |
| Cytomap | 5q13.2 | 5q13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | microtubule-associated protein 1Bprotein phosphatase 1, regulatory subunit 102 | microtubule-associated protein 1Bprotein phosphatase 1, regulatory subunit 102 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P46821 | P46821 | |
| Ensembl transtripts involved in fusion gene | ENST00000296755, ENST00000504183, | ENST00000296755, ENST00000504183, | |
| Fusion gene scores | * DoF score | 9 X 8 X 5=360 | 6 X 8 X 2=96 |
| # samples | 11 | 8 | |
| ** MAII score | log2(11/360*10)=-1.71049338280502 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/96*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MAP1B [Title/Abstract] AND MAP1B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | MAP1B | GO:0009987 | cellular process | 19567321 |
| Tgene | MAP1B | GO:0009987 | cellular process | 19567321 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF953347 | MAP1B | chr5 | 71493015 | - | MAP1B | chr5 | 71492960 | + | ||
| ChiTaRS3.1 | BE855959 | MAP1B | chr5 | 71491085 | - | MAP1B | chr5 | 71492504 | - | ||
| ChiTaRS3.1 | DB382833 | MAP1B | chr5 | 71490889 | - | MAP1B | chr5 | 71501186 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000296755 | ENST00000296755 | MAP1B | chr5 | 71493015 | - | MAP1B | chr5 | 71492960 | + |
| 5CDS-intron | ENST00000296755 | ENST00000504183 | MAP1B | chr5 | 71493015 | - | MAP1B | chr5 | 71492960 | + |
| intron-3CDS | ENST00000504183 | ENST00000296755 | MAP1B | chr5 | 71493015 | - | MAP1B | chr5 | 71492960 | + |
| intron-intron | ENST00000504183 | ENST00000504183 | MAP1B | chr5 | 71493015 | - | MAP1B | chr5 | 71492960 | + |
| Frame-shift | ENST00000296755 | ENST00000296755 | MAP1B | chr5 | 71491085 | - | MAP1B | chr5 | 71492504 | - |
| 5CDS-intron | ENST00000296755 | ENST00000504183 | MAP1B | chr5 | 71491085 | - | MAP1B | chr5 | 71492504 | - |
| intron-3CDS | ENST00000504183 | ENST00000296755 | MAP1B | chr5 | 71491085 | - | MAP1B | chr5 | 71492504 | - |
| intron-intron | ENST00000504183 | ENST00000504183 | MAP1B | chr5 | 71491085 | - | MAP1B | chr5 | 71492504 | - |
| 5CDS-3UTR | ENST00000296755 | ENST00000296755 | MAP1B | chr5 | 71490889 | - | MAP1B | chr5 | 71501186 | - |
| 5CDS-intron | ENST00000296755 | ENST00000504183 | MAP1B | chr5 | 71490889 | - | MAP1B | chr5 | 71501186 | - |
| intron-3UTR | ENST00000504183 | ENST00000296755 | MAP1B | chr5 | 71490889 | - | MAP1B | chr5 | 71501186 | - |
| intron-intron | ENST00000504183 | ENST00000504183 | MAP1B | chr5 | 71490889 | - | MAP1B | chr5 | 71501186 | - |
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FusionProtFeatures for MAP1B_MAP1B |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MAP1B | MAP1B |