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Fusion gene ID: 20660 |
FusionGeneSummary for MALAT1_RPL13 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: MALAT1_RPL13 | Fusion gene ID: 20660 | Hgene | Tgene | Gene symbol | MALAT1 | RPL13 | Gene ID | 378938 | 28998 |
| Gene name | metastasis associated lung adenocarcinoma transcript 1 | mitochondrial ribosomal protein L13 | |
| Synonyms | HCN|LINC00047|NCRNA00047|NEAT2|PRO2853 | L13|L13A|L13mt|RPL13|RPML13 | |
| Cytomap | 11q13.1 | 8q24.12 | |
| Type of gene | ncRNA | protein-coding | |
| Description | hepcarcinlong intergenic non-protein coding RNA 47metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)nuclear enriched abundant transcript 2nuclear paraspeckle assembly transcript 2 (non-protein coding) | 39S ribosomal protein L13, mitochondrialMRP-L13mitochondrial large ribosomal subunit protein uL13m | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | P26373 | ||
| Ensembl transtripts involved in fusion gene | ENST00000534336, | ENST00000311528, ENST00000567815, ENST00000452368, ENST00000393099, | |
| Fusion gene scores | * DoF score | 83 X 128 X 5=53120 | 7 X 7 X 2=98 |
| # samples | 141 | 7 | |
| ** MAII score | log2(141/53120*10)=-5.23548807894813 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/98*10)=-0.485426827170242 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: MALAT1 [Title/Abstract] AND RPL13 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | CR748210 | MALAT1 | chr11 | 65268002 | + | RPL13 | chr16 | 89629402 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000534336 | ENST00000311528 | MALAT1 | chr11 | 65268002 | + | RPL13 | chr16 | 89629402 | + |
| 3UTR-3CDS | ENST00000534336 | ENST00000567815 | MALAT1 | chr11 | 65268002 | + | RPL13 | chr16 | 89629402 | + |
| 3UTR-3CDS | ENST00000534336 | ENST00000452368 | MALAT1 | chr11 | 65268002 | + | RPL13 | chr16 | 89629402 | + |
| 3UTR-3CDS | ENST00000534336 | ENST00000393099 | MALAT1 | chr11 | 65268002 | + | RPL13 | chr16 | 89629402 | + |
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FusionProtFeatures for MALAT1_RPL13 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| MALAT1 | RPL13 |