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Fusion gene ID: 20418 |
FusionGeneSummary for LUC7L_SLC27A5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LUC7L_SLC27A5 | Fusion gene ID: 20418 | Hgene | Tgene | Gene symbol | LUC7L | SLC27A5 | Gene ID | 55692 | 10998 |
| Gene name | LUC7 like | solute carrier family 27 member 5 | |
| Synonyms | LUC7B1|Luc7|SR+89|hLuc7B1 | ACSB|ACSVL6|BACS|BAL|FACVL3|FATP-5|FATP5|VLACSR|VLCS-H2|VLCSH2 | |
| Cytomap | 16p13.3 | 19q13.43 | |
| Type of gene | protein-coding | protein-coding | |
| Description | putative RNA-binding protein Luc7-like 1putative SR protein LUC7B1sarcoplasmic reticulum protein LUC7B1 | bile acyl-CoA synthetaseBA-CoA ligaseVLACS-relatedbile acid-CoA ligasecholate--CoA ligasefatty acid transport protein 5fatty-acid-Coenzyme A ligase, very long-chain 3solute carrier family 27 (fatty acid transporter), member 5very long-chain acyl-C | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9NQ29 | Q9Y2P5 | |
| Ensembl transtripts involved in fusion gene | ENST00000293872, ENST00000337351, ENST00000397783, ENST00000397780, ENST00000494366, | ENST00000594786, ENST00000599700, ENST00000263093, ENST00000601355, | |
| Fusion gene scores | * DoF score | 9 X 9 X 7=567 | 3 X 2 X 3=18 |
| # samples | 12 | 3 | |
| ** MAII score | log2(12/567*10)=-2.24031432933371 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: LUC7L [Title/Abstract] AND SLC27A5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | SLC27A5 | GO:0000038 | very long-chain fatty acid metabolic process | 10479480 |
| Tgene | SLC27A5 | GO:0006699 | bile acid biosynthetic process | 11980911 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BLCA | TCGA-4Z-AA87-01A | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000293872 | ENST00000594786 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000293872 | ENST00000599700 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000293872 | ENST00000263093 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000293872 | ENST00000601355 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000337351 | ENST00000594786 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000337351 | ENST00000599700 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000337351 | ENST00000263093 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000337351 | ENST00000601355 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000397783 | ENST00000594786 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000397783 | ENST00000599700 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000397783 | ENST00000263093 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000397783 | ENST00000601355 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000397780 | ENST00000594786 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000397780 | ENST00000599700 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000397780 | ENST00000263093 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5CDS-intron | ENST00000397780 | ENST00000601355 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5UTR-intron | ENST00000494366 | ENST00000594786 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5UTR-intron | ENST00000494366 | ENST00000599700 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5UTR-intron | ENST00000494366 | ENST00000263093 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
| 5UTR-intron | ENST00000494366 | ENST00000601355 | LUC7L | chr16 | 270648 | - | SLC27A5 | chr19 | 59012777 | - |
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FusionProtFeatures for LUC7L_SLC27A5 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| LUC7L | SLC27A5 |