|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 20062 |
FusionGeneSummary for LRBA_HFE2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LRBA_HFE2 | Fusion gene ID: 20062 | Hgene | Tgene | Gene symbol | LRBA | HFE2 | Gene ID | 987 |
| Gene name | LPS responsive beige-like anchor protein | ||
| Synonyms | BGL|CDC4L|CVID8|LAB300|LBA | ||
| Cytomap | 4q31.3 | ||
| Type of gene | protein-coding | ||
| Description | lipopolysaccharide-responsive and beige-like anchor proteinCDC4-like proteinLPS-responsive vesicle trafficking, beach and anchor containingvesicle trafficking, beach and anchor containing | ||
| Modification date | 20180519 | ||
| UniProtAcc | P50851 | Q6ZVN8 | |
| Ensembl transtripts involved in fusion gene | ENST00000535741, ENST00000510413, ENST00000503716, ENST00000357115, ENST00000507224, | ENST00000357836, ENST00000336751, ENST00000497365, ENST00000475797, | |
| Fusion gene scores | * DoF score | 16 X 15 X 12=2880 | 4 X 2 X 4=32 |
| # samples | 22 | 4 | |
| ** MAII score | log2(22/2880*10)=-3.71049338280502 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: LRBA [Title/Abstract] AND HFE2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |