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Fusion gene ID: 1952 |
FusionGeneSummary for ANP32A_C1orf87 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ANP32A_C1orf87 | Fusion gene ID: 1952 | Hgene | Tgene | Gene symbol | ANP32A | C1orf87 | Gene ID | 8125 | 127795 |
| Gene name | acidic nuclear phosphoprotein 32 family member A | chromosome 1 open reading frame 87 | |
| Synonyms | C15orf1|HPPCn|I1PP2A|LANP|MAPM|PHAP1|PHAPI|PP32 | CREF | |
| Cytomap | 15q23 | 1p32.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | acidic leucine-rich nuclear phosphoprotein 32 family member Aacidic (leucine-rich) nuclear phosphoprotein 32 family, member Aacidic nuclear phosphoprotein pp32cerebellar leucine rich acidic nuclear proteinhepatopoietin Cninhibitor-1 of protein phosph | uncharacterized protein C1orf87carcinoma-related EF-hand protein | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | P39687 | Q8N0U7 | |
| Ensembl transtripts involved in fusion gene | ENST00000465139, ENST00000483551, ENST00000560303, | ENST00000486478, ENST00000450089, ENST00000371201, ENST00000395552, | |
| Fusion gene scores | * DoF score | 5 X 5 X 2=50 | 5 X 5 X 5=125 |
| # samples | 5 | 5 | |
| ** MAII score | log2(5/50*10)=0 | log2(5/125*10)=-1.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ANP32A [Title/Abstract] AND C1orf87 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ANP32A | GO:0006913 | nucleocytoplasmic transport | 11729309 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | T20169 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000465139 | ENST00000486478 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| intron-intron | ENST00000465139 | ENST00000450089 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| intron-intron | ENST00000465139 | ENST00000371201 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| intron-intron | ENST00000465139 | ENST00000395552 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| intron-intron | ENST00000483551 | ENST00000486478 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| intron-intron | ENST00000483551 | ENST00000450089 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| intron-intron | ENST00000483551 | ENST00000371201 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| intron-intron | ENST00000483551 | ENST00000395552 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| intron-intron | ENST00000560303 | ENST00000486478 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| intron-intron | ENST00000560303 | ENST00000450089 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| intron-intron | ENST00000560303 | ENST00000371201 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
| intron-intron | ENST00000560303 | ENST00000395552 | ANP32A | chr15 | 69071722 | - | C1orf87 | chr1 | 60458727 | + |
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FusionProtFeatures for ANP32A_C1orf87 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ANP32A | C1orf87 |