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Fusion gene ID: 18945 |
FusionGeneSummary for KIRREL_PYHIN1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KIRREL_PYHIN1 | Fusion gene ID: 18945 | Hgene | Tgene | Gene symbol | KIRREL | PYHIN1 | Gene ID | 149628 |
| Gene name | pyrin and HIN domain family member 1 | ||
| Synonyms | IFIX | ||
| Cytomap | 1q23.1 | ||
| Type of gene | protein-coding | ||
| Description | pyrin and HIN domain-containing protein 1interferon-inducible protein X | ||
| Modification date | 20180519 | ||
| UniProtAcc | Q6K0P9 | ||
| Ensembl transtripts involved in fusion gene | ENST00000392272, ENST00000368173, ENST00000360089, ENST00000359209, ENST00000416935, ENST00000368172, | ENST00000368140, ENST00000368138, ENST00000392254, ENST00000392252, ENST00000368135, ENST00000485134, | |
| Fusion gene scores | * DoF score | 9 X 4 X 6=216 | 2 X 2 X 2=8 |
| # samples | 9 | 2 | |
| ** MAII score | log2(9/216*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: KIRREL [Title/Abstract] AND PYHIN1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |