|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 18670 |
FusionGeneSummary for KIAA1217_DNAJC17 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KIAA1217_DNAJC17 | Fusion gene ID: 18670 | Hgene | Tgene | Gene symbol | KIAA1217 | DNAJC17 | Gene ID | 56243 | 55192 |
| Gene name | KIAA1217 | DnaJ heat shock protein family (Hsp40) member C17 | |
| Synonyms | ETL4|SKT | - | |
| Cytomap | 10p12.2-p12.1 | 15q15.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sickle tail protein homologlikely orthologue of Mus musculus enhancer trap locus 4 | dnaJ homolog subfamily C member 17DnaJ (Hsp40) homolog, subfamily C, member 17 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q5T5P2 | Q9NVM6 | |
| Ensembl transtripts involved in fusion gene | ENST00000376462, ENST00000481700, ENST00000458595, ENST00000376454, ENST00000376452, ENST00000430453, ENST00000307544, ENST00000396446, ENST00000396445, ENST00000376451, | ENST00000220496, ENST00000558727, | |
| Fusion gene scores | * DoF score | 10 X 10 X 6=600 | 2 X 2 X 2=8 |
| # samples | 11 | 2 | |
| ** MAII score | log2(11/600*10)=-2.44745897697122 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: KIAA1217 [Title/Abstract] AND DNAJC17 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF091043 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000376462 | ENST00000220496 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000376462 | ENST00000558727 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000481700 | ENST00000220496 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000481700 | ENST00000558727 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000458595 | ENST00000220496 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000458595 | ENST00000558727 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000376454 | ENST00000220496 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000376454 | ENST00000558727 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000376452 | ENST00000220496 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000376452 | ENST00000558727 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000430453 | ENST00000220496 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000430453 | ENST00000558727 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000307544 | ENST00000220496 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000307544 | ENST00000558727 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000396446 | ENST00000220496 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000396446 | ENST00000558727 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000396445 | ENST00000220496 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000396445 | ENST00000558727 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000376451 | ENST00000220496 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
| intron-intron | ENST00000376451 | ENST00000558727 | KIAA1217 | chr10 | 24824992 | + | DNAJC17 | chr15 | 41064303 | - |
Top |
FusionProtFeatures for KIAA1217_DNAJC17 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KIAA1217 | DNAJC17 |