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Fusion gene ID: 18667 |
FusionGeneSummary for KIAA1211_SCFD2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KIAA1211_SCFD2 | Fusion gene ID: 18667 | Hgene | Tgene | Gene symbol | KIAA1211 | SCFD2 | Gene ID | 57482 | 152579 |
| Gene name | KIAA1211 | sec1 family domain containing 2 | |
| Synonyms | - | STXBP1L1 | |
| Cytomap | 4q12 | 4q12 | |
| Type of gene | protein-coding | protein-coding | |
| Description | uncharacterized protein KIAA1211 | sec1 family domain-containing protein 2syntaxin binding protein 1-like 1 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q6ZU35 | Q8WU76 | |
| Ensembl transtripts involved in fusion gene | ENST00000264229, ENST00000541073, ENST00000504228, ENST00000505410, | ENST00000401642, ENST00000388940, | |
| Fusion gene scores | * DoF score | 6 X 4 X 4=96 | 10 X 8 X 10=800 |
| # samples | 6 | 11 | |
| ** MAII score | log2(6/96*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(11/800*10)=-2.86249647625006 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: KIAA1211 [Title/Abstract] AND SCFD2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LGG | TCGA-HT-A5R7-01A | KIAA1211 | chr4 | 57045596 | + | SCFD2 | chr4 | 53773758 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000264229 | ENST00000401642 | KIAA1211 | chr4 | 57045596 | + | SCFD2 | chr4 | 53773758 | - |
| 5UTR-intron | ENST00000264229 | ENST00000388940 | KIAA1211 | chr4 | 57045596 | + | SCFD2 | chr4 | 53773758 | - |
| intron-3CDS | ENST00000541073 | ENST00000401642 | KIAA1211 | chr4 | 57045596 | + | SCFD2 | chr4 | 53773758 | - |
| intron-intron | ENST00000541073 | ENST00000388940 | KIAA1211 | chr4 | 57045596 | + | SCFD2 | chr4 | 53773758 | - |
| intron-3CDS | ENST00000504228 | ENST00000401642 | KIAA1211 | chr4 | 57045596 | + | SCFD2 | chr4 | 53773758 | - |
| intron-intron | ENST00000504228 | ENST00000388940 | KIAA1211 | chr4 | 57045596 | + | SCFD2 | chr4 | 53773758 | - |
| intron-3CDS | ENST00000505410 | ENST00000401642 | KIAA1211 | chr4 | 57045596 | + | SCFD2 | chr4 | 53773758 | - |
| intron-intron | ENST00000505410 | ENST00000388940 | KIAA1211 | chr4 | 57045596 | + | SCFD2 | chr4 | 53773758 | - |
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FusionProtFeatures for KIAA1211_SCFD2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KIAA1211 | SCFD2 |