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Fusion gene ID: 18575 |
FusionGeneSummary for KIAA0232_USP54 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KIAA0232_USP54 | Fusion gene ID: 18575 | Hgene | Tgene | Gene symbol | KIAA0232 | USP54 | Gene ID | 9778 | 159195 |
| Gene name | KIAA0232 | ubiquitin specific peptidase 54 | |
| Synonyms | - | C10orf29|bA137L10.3|bA137L10.4 | |
| Cytomap | 4p16.1 | 10q22.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | uncharacterized protein KIAA0232 | inactive ubiquitin carboxyl-terminal hydrolase 54inactive ubiquitin-specific peptidase 54ubiquitin specific protease 54ubiquitin specific proteinase 54 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q92628 | Q70EL1 | |
| Ensembl transtripts involved in fusion gene | ENST00000503278, ENST00000425103, ENST00000307659, | ENST00000339859, ENST00000408019, ENST00000428547, ENST00000394811, ENST00000497106, ENST00000422491, ENST00000319786, | |
| Fusion gene scores | * DoF score | 8 X 7 X 4=224 | 5 X 6 X 2=60 |
| # samples | 8 | 6 | |
| ** MAII score | log2(8/224*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/60*10)=0 | |
| Context | PubMed: KIAA0232 [Title/Abstract] AND USP54 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BQ376517 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000503278 | ENST00000339859 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-3CDS | ENST00000503278 | ENST00000408019 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-3CDS | ENST00000503278 | ENST00000428547 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-5UTR | ENST00000503278 | ENST00000394811 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-5UTR | ENST00000503278 | ENST00000497106 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-5UTR | ENST00000503278 | ENST00000422491 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-intron | ENST00000503278 | ENST00000319786 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-3CDS | ENST00000425103 | ENST00000339859 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-3CDS | ENST00000425103 | ENST00000408019 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-3CDS | ENST00000425103 | ENST00000428547 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-5UTR | ENST00000425103 | ENST00000394811 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-5UTR | ENST00000425103 | ENST00000497106 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-5UTR | ENST00000425103 | ENST00000422491 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-intron | ENST00000425103 | ENST00000319786 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-3CDS | ENST00000307659 | ENST00000339859 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-3CDS | ENST00000307659 | ENST00000408019 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-3CDS | ENST00000307659 | ENST00000428547 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-5UTR | ENST00000307659 | ENST00000394811 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-5UTR | ENST00000307659 | ENST00000497106 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-5UTR | ENST00000307659 | ENST00000422491 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
| intron-intron | ENST00000307659 | ENST00000319786 | KIAA0232 | chr4 | 6812809 | + | USP54 | chr10 | 75277475 | - |
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FusionProtFeatures for KIAA0232_USP54 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KIAA0232 | USP54 |