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Fusion gene ID: 1843 |
FusionGeneSummary for ANKRD33B_ANKH |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ANKRD33B_ANKH | Fusion gene ID: 1843 | Hgene | Tgene | Gene symbol | ANKRD33B | ANKH | Gene ID | 651746 | 56172 |
| Gene name | ankyrin repeat domain 33B | ANKH inorganic pyrophosphate transport regulator | |
| Synonyms | - | ANK|CCAL2|CMDJ|CPPDD|HANK|MANK|SLC62A1 | |
| Cytomap | 5p15.2 | 5p15.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ankyrin repeat domain-containing protein 33BAnkyrin repeat domain-containing protein LOC651746 | progressive ankylosis protein homologankylosis, progressive homolog | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | A6NCL7 | Q9HCJ1 | |
| Ensembl transtripts involved in fusion gene | ENST00000296657, | ENST00000284268, ENST00000535119, ENST00000503939, | |
| Fusion gene scores | * DoF score | 5 X 1 X 4=20 | 9 X 7 X 5=315 |
| # samples | 5 | 9 | |
| ** MAII score | log2(5/20*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(9/315*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ANKRD33B [Title/Abstract] AND ANKH [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-DX-A1KZ-01A | ANKRD33B | chr5 | 10564945 | + | ANKH | chr5 | 14769300 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000296657 | ENST00000284268 | ANKRD33B | chr5 | 10564945 | + | ANKH | chr5 | 14769300 | - |
| 5CDS-intron | ENST00000296657 | ENST00000535119 | ANKRD33B | chr5 | 10564945 | + | ANKH | chr5 | 14769300 | - |
| 5CDS-intron | ENST00000296657 | ENST00000503939 | ANKRD33B | chr5 | 10564945 | + | ANKH | chr5 | 14769300 | - |
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FusionProtFeatures for ANKRD33B_ANKH |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ANKRD33B | ANKH |