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Fusion gene ID: 18270 |
FusionGeneSummary for KCNIP4_KIF1A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KCNIP4_KIF1A | Fusion gene ID: 18270 | Hgene | Tgene | Gene symbol | KCNIP4 | KIF1A | Gene ID | 80333 | 547 |
| Gene name | potassium voltage-gated channel interacting protein 4 | kinesin family member 1A | |
| Synonyms | CALP|KCHIP4 | ATSV|C2orf20|HSN2C|MRD9|SPG30|UNC104 | |
| Cytomap | 4p15.31-p15.2 | 2q37.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | Kv channel-interacting protein 4Kv channel interacting protein 4a-type potassium channel modulatory protein 4calsenilin-like protein | kinesin-like protein KIF1Aaxonal transporter of synaptic vesicleskinesin, heavy chain, member 1A, homolog of mousemicrotubule-based motor KIF1Aunc-104- and KIF1A-related protein | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q6PIL6 | Q12756 | |
| Ensembl transtripts involved in fusion gene | ENST00000382148, ENST00000447367, ENST00000382150, ENST00000382152, ENST00000509207, ENST00000382149, ENST00000359001, | ENST00000320389, ENST00000498729, | |
| Fusion gene scores | * DoF score | 5 X 5 X 2=50 | 5 X 6 X 2=60 |
| # samples | 5 | 6 | |
| ** MAII score | log2(5/50*10)=0 | log2(6/60*10)=0 | |
| Context | PubMed: KCNIP4 [Title/Abstract] AND KIF1A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | U73665 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000382148 | ENST00000320389 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000382148 | ENST00000498729 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000447367 | ENST00000320389 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000447367 | ENST00000498729 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000382150 | ENST00000320389 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000382150 | ENST00000498729 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000382152 | ENST00000320389 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000382152 | ENST00000498729 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000509207 | ENST00000320389 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000509207 | ENST00000498729 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000382149 | ENST00000320389 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000382149 | ENST00000498729 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000359001 | ENST00000320389 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
| intron-intron | ENST00000359001 | ENST00000498729 | KCNIP4 | chr4 | 20876982 | - | KIF1A | chr2 | 241713790 | + |
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FusionProtFeatures for KCNIP4_KIF1A |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KCNIP4 | KIF1A |