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Fusion gene ID: 18207 |
FusionGeneSummary for KATNBL1_KATNBL1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KATNBL1_KATNBL1 | Fusion gene ID: 18207 | Hgene | Tgene | Gene symbol | KATNBL1 | KATNBL1 | Gene ID | 79768 | 79768 |
| Gene name | katanin regulatory subunit B1 like 1 | katanin regulatory subunit B1 like 1 | |
| Synonyms | C15orf29 | C15orf29 | |
| Cytomap | 15q14 | 15q14 | |
| Type of gene | protein-coding | protein-coding | |
| Description | KATNB1-like protein 1katanin p80 subunit B-like 1 | KATNB1-like protein 1katanin p80 subunit B-like 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q9H079 | Q9H079 | |
| Ensembl transtripts involved in fusion gene | ENST00000256544, ENST00000560915, | ENST00000256544, ENST00000560915, | |
| Fusion gene scores | * DoF score | 6 X 5 X 3=90 | 1 X 1 X 1=1 |
| # samples | 6 | 1 | |
| ** MAII score | log2(6/90*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: KATNBL1 [Title/Abstract] AND KATNBL1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | KATNBL1 | GO:0051495 | positive regulation of cytoskeleton organization | 26929214 |
| Tgene | KATNBL1 | GO:0051495 | positive regulation of cytoskeleton organization | 26929214 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BX094467 | KATNBL1 | chr15 | 34435639 | - | KATNBL1 | chr15 | 34436822 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000256544 | ENST00000256544 | KATNBL1 | chr15 | 34435639 | - | KATNBL1 | chr15 | 34436822 | - |
| intron-intron | ENST00000256544 | ENST00000560915 | KATNBL1 | chr15 | 34435639 | - | KATNBL1 | chr15 | 34436822 | - |
| intron-intron | ENST00000560915 | ENST00000256544 | KATNBL1 | chr15 | 34435639 | - | KATNBL1 | chr15 | 34436822 | - |
| intron-intron | ENST00000560915 | ENST00000560915 | KATNBL1 | chr15 | 34435639 | - | KATNBL1 | chr15 | 34436822 | - |
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FusionProtFeatures for KATNBL1_KATNBL1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KATNBL1 | KATNBL1 |