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Fusion gene ID: 1768 |
FusionGeneSummary for ANKRD11_FANCA |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ANKRD11_FANCA | Fusion gene ID: 1768 | Hgene | Tgene | Gene symbol | ANKRD11 | FANCA | Gene ID | 29123 | 2175 |
| Gene name | ankyrin repeat domain 11 | FA complementation group A | |
| Synonyms | ANCO-1|ANCO1|LZ16|T13 | FA|FA-H|FA1|FAA|FACA|FAH|FANCH | |
| Cytomap | 16q24.3 | 16q24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ankyrin repeat domain-containing protein 11ankyrin repeat-containing cofactor 1nasopharyngeal carcinoma susceptibility proteintruncated ankyrin repeat domain 11 aberrant transcript 1truncated ankyrin repeat domain 11 aberrant transcript 2 | Fanconi anemia group A proteinFanconi anemia complementation group AFanconi anemia, complementation group HFanconi anemia, type 1 | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | Q6UB99 | O15360 | |
| Ensembl transtripts involved in fusion gene | ENST00000378330, ENST00000301030, ENST00000563291, ENST00000567736, | ENST00000389301, ENST00000568369, ENST00000567284, ENST00000389302, ENST00000563673, ENST00000534992, ENST00000543736, | |
| Fusion gene scores | * DoF score | 29 X 15 X 15=6525 | 6 X 9 X 5=270 |
| # samples | 37 | 10 | |
| ** MAII score | log2(37/6525*10)=-4.1403807258283 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/270*10)=-1.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ANKRD11 [Title/Abstract] AND FANCA [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | ESCA | TCGA-L5-A8NI-01A | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| TCGA | RV | LUAD | TCGA-97-8176-01A | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| TCGA | RV | STAD | TCGA-BR-8485-01A | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| TCGA | RV | STAD | TCGA-BR-A4QI-01A | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-3CDS | ENST00000378330 | ENST00000389301 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-3CDS | ENST00000378330 | ENST00000568369 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000378330 | ENST00000567284 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000378330 | ENST00000389302 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000378330 | ENST00000563673 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000378330 | ENST00000534992 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000378330 | ENST00000543736 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-3CDS | ENST00000301030 | ENST00000389301 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-3CDS | ENST00000301030 | ENST00000568369 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000301030 | ENST00000567284 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000301030 | ENST00000389302 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000301030 | ENST00000563673 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000301030 | ENST00000534992 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000301030 | ENST00000543736 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-3CDS | ENST00000563291 | ENST00000389301 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-3CDS | ENST00000563291 | ENST00000568369 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000563291 | ENST00000567284 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000563291 | ENST00000389302 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000563291 | ENST00000563673 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000563291 | ENST00000534992 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000563291 | ENST00000543736 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-3CDS | ENST00000567736 | ENST00000389301 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-3CDS | ENST00000567736 | ENST00000568369 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000567736 | ENST00000567284 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000567736 | ENST00000389302 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000567736 | ENST00000563673 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000567736 | ENST00000534992 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000567736 | ENST00000543736 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-3CDS | ENST00000378330 | ENST00000389301 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-3CDS | ENST00000378330 | ENST00000568369 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000378330 | ENST00000567284 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000378330 | ENST00000389302 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000378330 | ENST00000563673 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000378330 | ENST00000534992 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000378330 | ENST00000543736 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-3CDS | ENST00000301030 | ENST00000389301 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-3CDS | ENST00000301030 | ENST00000568369 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000301030 | ENST00000567284 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000301030 | ENST00000389302 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000301030 | ENST00000563673 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000301030 | ENST00000534992 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-intron | ENST00000301030 | ENST00000543736 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-3CDS | ENST00000563291 | ENST00000389301 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-3CDS | ENST00000563291 | ENST00000568369 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000563291 | ENST00000567284 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000563291 | ENST00000389302 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000563291 | ENST00000563673 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000563291 | ENST00000534992 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000563291 | ENST00000543736 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-3CDS | ENST00000567736 | ENST00000389301 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-3CDS | ENST00000567736 | ENST00000568369 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000567736 | ENST00000567284 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000567736 | ENST00000389302 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000567736 | ENST00000563673 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000567736 | ENST00000534992 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| intron-intron | ENST00000567736 | ENST00000543736 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89818630 | - |
| 5UTR-3CDS | ENST00000378330 | ENST00000389301 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-3CDS | ENST00000378330 | ENST00000568369 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-intron | ENST00000378330 | ENST00000567284 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-intron | ENST00000378330 | ENST00000389302 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-intron | ENST00000378330 | ENST00000563673 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-intron | ENST00000378330 | ENST00000534992 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-intron | ENST00000378330 | ENST00000543736 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-3CDS | ENST00000301030 | ENST00000389301 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-3CDS | ENST00000301030 | ENST00000568369 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-intron | ENST00000301030 | ENST00000567284 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-intron | ENST00000301030 | ENST00000389302 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-intron | ENST00000301030 | ENST00000563673 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-intron | ENST00000301030 | ENST00000534992 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-intron | ENST00000301030 | ENST00000543736 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-3CDS | ENST00000563291 | ENST00000389301 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-3CDS | ENST00000563291 | ENST00000568369 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-intron | ENST00000563291 | ENST00000567284 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-intron | ENST00000563291 | ENST00000389302 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-intron | ENST00000563291 | ENST00000563673 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-intron | ENST00000563291 | ENST00000534992 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-intron | ENST00000563291 | ENST00000543736 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-3CDS | ENST00000567736 | ENST00000389301 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-3CDS | ENST00000567736 | ENST00000568369 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-intron | ENST00000567736 | ENST00000567284 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-intron | ENST00000567736 | ENST00000389302 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-intron | ENST00000567736 | ENST00000563673 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-intron | ENST00000567736 | ENST00000534992 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| intron-intron | ENST00000567736 | ENST00000543736 | ANKRD11 | chr16 | 89556653 | - | FANCA | chr16 | 89849510 | - |
| 5UTR-3CDS | ENST00000378330 | ENST00000389301 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-3CDS | ENST00000378330 | ENST00000568369 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-5UTR | ENST00000378330 | ENST00000567284 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-intron | ENST00000378330 | ENST00000389302 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-intron | ENST00000378330 | ENST00000563673 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-intron | ENST00000378330 | ENST00000534992 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-intron | ENST00000378330 | ENST00000543736 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-3CDS | ENST00000301030 | ENST00000389301 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-3CDS | ENST00000301030 | ENST00000568369 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-5UTR | ENST00000301030 | ENST00000567284 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-intron | ENST00000301030 | ENST00000389302 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-intron | ENST00000301030 | ENST00000563673 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-intron | ENST00000301030 | ENST00000534992 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| 5UTR-intron | ENST00000301030 | ENST00000543736 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-3CDS | ENST00000563291 | ENST00000389301 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-3CDS | ENST00000563291 | ENST00000568369 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-5UTR | ENST00000563291 | ENST00000567284 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-intron | ENST00000563291 | ENST00000389302 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-intron | ENST00000563291 | ENST00000563673 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-intron | ENST00000563291 | ENST00000534992 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-intron | ENST00000563291 | ENST00000543736 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-3CDS | ENST00000567736 | ENST00000389301 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-3CDS | ENST00000567736 | ENST00000568369 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-5UTR | ENST00000567736 | ENST00000567284 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-intron | ENST00000567736 | ENST00000389302 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-intron | ENST00000567736 | ENST00000563673 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-intron | ENST00000567736 | ENST00000534992 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
| intron-intron | ENST00000567736 | ENST00000543736 | ANKRD11 | chr16 | 89484692 | - | FANCA | chr16 | 89838222 | - |
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FusionProtFeatures for ANKRD11_FANCA |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ANKRD11 | FANCA |