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Fusion gene ID: 1752 |
FusionGeneSummary for ANKRD10_CPNE4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ANKRD10_CPNE4 | Fusion gene ID: 1752 | Hgene | Tgene | Gene symbol | ANKRD10 | CPNE4 | Gene ID | 55608 | 131034 |
| Gene name | ankyrin repeat domain 10 | copine 4 | |
| Synonyms | - | COPN4|CPN4 | |
| Cytomap | 13q34 | 3q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ankyrin repeat domain-containing protein 10 | copine-4copine 8copine IV | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q9NXR5 | Q96A23 | |
| Ensembl transtripts involved in fusion gene | ENST00000267339, ENST00000375758, ENST00000489973, ENST00000310847, | ENST00000512055, ENST00000429747, ENST00000512332, ENST00000511604, ENST00000502818, ENST00000503204, | |
| Fusion gene scores | * DoF score | 6 X 5 X 2=60 | 10 X 7 X 5=350 |
| # samples | 6 | 10 | |
| ** MAII score | log2(6/60*10)=0 | log2(10/350*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ANKRD10 [Title/Abstract] AND CPNE4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BE005082 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000267339 | ENST00000512055 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000267339 | ENST00000429747 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000267339 | ENST00000512332 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000267339 | ENST00000511604 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000267339 | ENST00000502818 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000267339 | ENST00000503204 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000375758 | ENST00000512055 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000375758 | ENST00000429747 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000375758 | ENST00000512332 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000375758 | ENST00000511604 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000375758 | ENST00000502818 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000375758 | ENST00000503204 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000489973 | ENST00000512055 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000489973 | ENST00000429747 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000489973 | ENST00000512332 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000489973 | ENST00000511604 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000489973 | ENST00000502818 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000489973 | ENST00000503204 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000310847 | ENST00000512055 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000310847 | ENST00000429747 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000310847 | ENST00000512332 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000310847 | ENST00000511604 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000310847 | ENST00000502818 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
| intron-intron | ENST00000310847 | ENST00000503204 | ANKRD10 | chr13 | 111535715 | - | CPNE4 | chr3 | 131804259 | + |
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FusionProtFeatures for ANKRD10_CPNE4 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ANKRD10 | CPNE4 |