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Fusion gene ID: 17063 |
FusionGeneSummary for IFI6_CTNS |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: IFI6_CTNS | Fusion gene ID: 17063 | Hgene | Tgene | Gene symbol | IFI6 | CTNS | Gene ID | 2537 | 1497 |
| Gene name | interferon alpha inducible protein 6 | cystinosin, lysosomal cystine transporter | |
| Synonyms | 6-16|FAM14C|G1P3|IFI-6-16|IFI616 | CTNS-LSB|PQLC4 | |
| Cytomap | 1p35.3 | 17p13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | interferon alpha-inducible protein 6interferon, alpha-inducible protein clone IFI-6-16interferon-induced protein 6-16 | cystinosincystinosis nephropathic | |
| Modification date | 20180523 | 20180527 | |
| UniProtAcc | P09912 | O60931 | |
| Ensembl transtripts involved in fusion gene | ENST00000361157, ENST00000339145, ENST00000362020, | ENST00000046640, ENST00000381870, ENST00000441220, ENST00000414524, ENST00000488623, ENST00000399306, | |
| Fusion gene scores | * DoF score | 6 X 5 X 2=60 | 1 X 1 X 1=1 |
| # samples | 6 | 1 | |
| ** MAII score | log2(6/60*10)=0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: IFI6 [Title/Abstract] AND CTNS [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AI954514 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000361157 | ENST00000046640 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000361157 | ENST00000381870 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000361157 | ENST00000441220 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000361157 | ENST00000414524 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000361157 | ENST00000488623 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-3UTR | ENST00000361157 | ENST00000399306 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000339145 | ENST00000046640 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000339145 | ENST00000381870 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000339145 | ENST00000441220 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000339145 | ENST00000414524 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000339145 | ENST00000488623 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-3UTR | ENST00000339145 | ENST00000399306 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000362020 | ENST00000046640 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000362020 | ENST00000381870 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000362020 | ENST00000441220 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000362020 | ENST00000414524 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-intron | ENST00000362020 | ENST00000488623 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
| intron-3UTR | ENST00000362020 | ENST00000399306 | IFI6 | chr1 | 27992686 | + | CTNS | chr17 | 3553661 | - |
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FusionProtFeatures for IFI6_CTNS |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| IFI6 | CTNS |