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Fusion gene ID: 16781 |
FusionGeneSummary for HS3ST1_CNTN5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HS3ST1_CNTN5 | Fusion gene ID: 16781 | Hgene | Tgene | Gene symbol | HS3ST1 | CNTN5 | Gene ID | 9957 | 53942 |
| Gene name | heparan sulfate-glucosamine 3-sulfotransferase 1 | contactin 5 | |
| Synonyms | 3OST|3OST1 | HNB-2s|NB-2 | |
| Cytomap | 4p15.33 | 11q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | heparan sulfate glucosamine 3-O-sulfotransferase 13-OST-1h3-OST-1heparan sulfate (glucosamine) 3-O-sulfotransferase 1heparan sulfate 3-O-sulfotransferase 1heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1heparin-glucosamine 3-O-sulfotransferase | contactin-5neural adhesion moleculeneural recognition molecule NB-2 | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | O14792 | O94779 | |
| Ensembl transtripts involved in fusion gene | ENST00000002596, | ENST00000527185, ENST00000528682, ENST00000524871, ENST00000418526, ENST00000279463, ENST00000524560, | |
| Fusion gene scores | * DoF score | 2 X 1 X 2=4 | 16 X 11 X 12=2112 |
| # samples | 2 | 16 | |
| ** MAII score | log2(2/4*10)=2.32192809488736 | log2(16/2112*10)=-3.72246602447109 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: HS3ST1 [Title/Abstract] AND CNTN5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | KIRC | TCGA-CZ-5982-01A | HS3ST1 | chr4 | 11430323 | - | CNTN5 | chr11 | 99426876 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-5UTR | ENST00000002596 | ENST00000527185 | HS3ST1 | chr4 | 11430323 | - | CNTN5 | chr11 | 99426876 | + |
| 5UTR-5UTR | ENST00000002596 | ENST00000528682 | HS3ST1 | chr4 | 11430323 | - | CNTN5 | chr11 | 99426876 | + |
| 5UTR-5UTR | ENST00000002596 | ENST00000524871 | HS3ST1 | chr4 | 11430323 | - | CNTN5 | chr11 | 99426876 | + |
| 5UTR-5UTR | ENST00000002596 | ENST00000418526 | HS3ST1 | chr4 | 11430323 | - | CNTN5 | chr11 | 99426876 | + |
| 5UTR-intron | ENST00000002596 | ENST00000279463 | HS3ST1 | chr4 | 11430323 | - | CNTN5 | chr11 | 99426876 | + |
| 5UTR-intron | ENST00000002596 | ENST00000524560 | HS3ST1 | chr4 | 11430323 | - | CNTN5 | chr11 | 99426876 | + |
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FusionProtFeatures for HS3ST1_CNTN5 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HS3ST1 | CNTN5 |