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Fusion gene ID: 16665 |
FusionGeneSummary for HOMEZ_FBXO34 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HOMEZ_FBXO34 | Fusion gene ID: 16665 | Hgene | Tgene | Gene symbol | HOMEZ | FBXO34 | Gene ID | 57594 | 55030 |
| Gene name | homeobox and leucine zipper encoding | F-box protein 34 | |
| Synonyms | KIAA1443 | CGI-301|Fbx34 | |
| Cytomap | 14q11.2 | 14q22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | homeobox and leucine zipper protein Homezhomeodomain leucine zipper-containing factor | F-box only protein 34protein CGI-301 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q8IX15 | Q9NWN3 | |
| Ensembl transtripts involved in fusion gene | ENST00000357460, ENST00000561013, ENST00000431326, ENST00000558278, | ENST00000313833, ENST00000555087, ENST00000440021, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 5 X 5 X 2=50 |
| # samples | 1 | 5 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(5/50*10)=0 | |
| Context | PubMed: HOMEZ [Title/Abstract] AND FBXO34 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | DA330803 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-5UTR | ENST00000357460 | ENST00000313833 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| intron-3UTR | ENST00000357460 | ENST00000555087 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| intron-5UTR | ENST00000357460 | ENST00000440021 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| 5UTR-5UTR | ENST00000561013 | ENST00000313833 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| 5UTR-3UTR | ENST00000561013 | ENST00000555087 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| 5UTR-5UTR | ENST00000561013 | ENST00000440021 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| intron-5UTR | ENST00000431326 | ENST00000313833 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| intron-3UTR | ENST00000431326 | ENST00000555087 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| intron-5UTR | ENST00000431326 | ENST00000440021 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| intron-5UTR | ENST00000558278 | ENST00000313833 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| intron-3UTR | ENST00000558278 | ENST00000555087 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
| intron-5UTR | ENST00000558278 | ENST00000440021 | HOMEZ | chr14 | 23768609 | - | FBXO34 | chr14 | 55817097 | + |
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FusionProtFeatures for HOMEZ_FBXO34 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HOMEZ | FBXO34 |