|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 16566 |
FusionGeneSummary for HNRNPD_NOL6 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: HNRNPD_NOL6 | Fusion gene ID: 16566 | Hgene | Tgene | Gene symbol | HNRNPD | NOL6 | Gene ID | 3184 | 65083 |
| Gene name | heterogeneous nuclear ribonucleoprotein D | nucleolar protein 6 | |
| Synonyms | AUF1|AUF1A|HNRPD|P37|hnRNPD0 | NRAP|UTP22|bA311H10.1 | |
| Cytomap | 4q21.22 | 9p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | heterogeneous nuclear ribonucleoprotein D0ARE-binding protein AUFI, type AAU-rich element RNA binding protein 1, 37kDahnRNP D0 | nucleolar protein 6nucleolar RNA-associated proteinnucleolar protein 6 (RNA-associated)nucleolar protein family 6 (RNA-associated) | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q14103 | Q9H6R4 | |
| Ensembl transtripts involved in fusion gene | ENST00000313899, ENST00000353341, ENST00000543098, ENST00000352301, ENST00000508119, ENST00000541060, | ENST00000379471, ENST00000464829, ENST00000455041, | |
| Fusion gene scores | * DoF score | 8 X 7 X 4=224 | 5 X 5 X 3=75 |
| # samples | 8 | 6 | |
| ** MAII score | log2(8/224*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/75*10)=-0.321928094887362 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: HNRNPD [Title/Abstract] AND NOL6 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BM835099 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000313899 | ENST00000379471 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000313899 | ENST00000464829 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000313899 | ENST00000455041 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-3CDS | ENST00000353341 | ENST00000379471 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000353341 | ENST00000464829 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000353341 | ENST00000455041 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-3CDS | ENST00000543098 | ENST00000379471 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000543098 | ENST00000464829 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000543098 | ENST00000455041 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-3CDS | ENST00000352301 | ENST00000379471 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000352301 | ENST00000464829 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000352301 | ENST00000455041 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-3CDS | ENST00000508119 | ENST00000379471 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000508119 | ENST00000464829 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000508119 | ENST00000455041 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-3CDS | ENST00000541060 | ENST00000379471 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000541060 | ENST00000464829 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
| intron-intron | ENST00000541060 | ENST00000455041 | HNRNPD | chr4 | 83294848 | - | NOL6 | chr9 | 33466171 | - |
Top |
FusionProtFeatures for HNRNPD_NOL6 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| HNRNPD | NOL6 |