|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 1613 |
FusionGeneSummary for AMMECR1L_TNFRSF10C |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: AMMECR1L_TNFRSF10C | Fusion gene ID: 1613 | Hgene | Tgene | Gene symbol | AMMECR1L | TNFRSF10C | Gene ID | 83607 | 8794 |
| Gene name | AMMECR1 like | TNF receptor superfamily member 10c | |
| Synonyms | - | CD263|DCR1|DCR1-TNFR|LIT|TRAIL-R3|TRAILR3|TRID | |
| Cytomap | 2q14.3 | 8p21.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | AMMECR1-like proteinAMME chromosomal region gene 1-like | tumor necrosis factor receptor superfamily member 10CTNF-related apoptosis-inducing ligand receptor 3antagonist decoy receptor for TRAIL/Apo-2Lcytotoxic TRAIL receptor-3decoy TRAIL receptor without death domaindecoy receptor 1lymphocyte inhibitor of | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | Q6DCA0 | O14798 | |
| Ensembl transtripts involved in fusion gene | ENST00000272647, ENST00000393001, | ENST00000397703, ENST00000520607, ENST00000356864, ENST00000540813, | |
| Fusion gene scores | * DoF score | 2 X 1 X 2=4 | 2 X 2 X 2=8 |
| # samples | 2 | 2 | |
| ** MAII score | log2(2/4*10)=2.32192809488736 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: AMMECR1L [Title/Abstract] AND TNFRSF10C [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-EJ-5524-01A | AMMECR1L | chr2 | 128641777 | - | TNFRSF10C | chr8 | 22969233 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5UTR-intron | ENST00000272647 | ENST00000397703 | AMMECR1L | chr2 | 128641777 | - | TNFRSF10C | chr8 | 22969233 | + |
| 5UTR-3UTR | ENST00000272647 | ENST00000520607 | AMMECR1L | chr2 | 128641777 | - | TNFRSF10C | chr8 | 22969233 | + |
| 5UTR-3UTR | ENST00000272647 | ENST00000356864 | AMMECR1L | chr2 | 128641777 | - | TNFRSF10C | chr8 | 22969233 | + |
| 5UTR-intron | ENST00000272647 | ENST00000540813 | AMMECR1L | chr2 | 128641777 | - | TNFRSF10C | chr8 | 22969233 | + |
| 5UTR-intron | ENST00000393001 | ENST00000397703 | AMMECR1L | chr2 | 128641777 | - | TNFRSF10C | chr8 | 22969233 | + |
| 5UTR-3UTR | ENST00000393001 | ENST00000520607 | AMMECR1L | chr2 | 128641777 | - | TNFRSF10C | chr8 | 22969233 | + |
| 5UTR-3UTR | ENST00000393001 | ENST00000356864 | AMMECR1L | chr2 | 128641777 | - | TNFRSF10C | chr8 | 22969233 | + |
| 5UTR-intron | ENST00000393001 | ENST00000540813 | AMMECR1L | chr2 | 128641777 | - | TNFRSF10C | chr8 | 22969233 | + |
Top |
FusionProtFeatures for AMMECR1L_TNFRSF10C |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| AMMECR1L | TNFRSF10C |