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Fusion gene ID: 15581 |
FusionGeneSummary for GSTA1_ZNF548 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GSTA1_ZNF548 | Fusion gene ID: 15581 | Hgene | Tgene | Gene symbol | GSTA1 | ZNF548 | Gene ID | 2938 | 147694 |
| Gene name | glutathione S-transferase alpha 1 | zinc finger protein 548 | |
| Synonyms | GST-epsilon|GST2|GSTA1-1|GTH1 | - | |
| Cytomap | 6p12.2 | 19q13.43 | |
| Type of gene | protein-coding | protein-coding | |
| Description | glutathione S-transferase A1GST HA subunit 1GST class-alpha member 1S-(hydroxyalkyl)glutathione lyase A1glutathione S-alkyltransferase A1glutathione S-aryltransferase A1glutathione S-transferase 2glutathione S-transferase Ha subunit 1testicular ti | zinc finger protein 548 | |
| Modification date | 20180519 | 20180522 | |
| UniProtAcc | P08263 | Q8NEK5 | |
| Ensembl transtripts involved in fusion gene | ENST00000493331, ENST00000334575, | ENST00000366197, ENST00000597400, ENST00000598895, ENST00000336128, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 1 X 1 X 1=1 |
| # samples | 1 | 1 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: GSTA1 [Title/Abstract] AND ZNF548 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | GSTA1 | GO:0006749 | glutathione metabolic process | 11851347|20606271 |
| Hgene | GSTA1 | GO:0043651 | linoleic acid metabolic process | 16624487 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AL096729 | GSTA1 | chr6 | 52663059 | - | ZNF548 | chr19 | 57913381 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000493331 | ENST00000366197 | GSTA1 | chr6 | 52663059 | - | ZNF548 | chr19 | 57913381 | + |
| intron-intron | ENST00000493331 | ENST00000597400 | GSTA1 | chr6 | 52663059 | - | ZNF548 | chr19 | 57913381 | + |
| intron-intron | ENST00000493331 | ENST00000598895 | GSTA1 | chr6 | 52663059 | - | ZNF548 | chr19 | 57913381 | + |
| intron-intron | ENST00000493331 | ENST00000336128 | GSTA1 | chr6 | 52663059 | - | ZNF548 | chr19 | 57913381 | + |
| intron-intron | ENST00000334575 | ENST00000366197 | GSTA1 | chr6 | 52663059 | - | ZNF548 | chr19 | 57913381 | + |
| intron-intron | ENST00000334575 | ENST00000597400 | GSTA1 | chr6 | 52663059 | - | ZNF548 | chr19 | 57913381 | + |
| intron-intron | ENST00000334575 | ENST00000598895 | GSTA1 | chr6 | 52663059 | - | ZNF548 | chr19 | 57913381 | + |
| intron-intron | ENST00000334575 | ENST00000336128 | GSTA1 | chr6 | 52663059 | - | ZNF548 | chr19 | 57913381 | + |
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FusionProtFeatures for GSTA1_ZNF548 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GSTA1 | ZNF548 |