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Fusion gene ID: 15118 |
FusionGeneSummary for GOSR2_GOSR2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GOSR2_GOSR2 | Fusion gene ID: 15118 | Hgene | Tgene | Gene symbol | GOSR2 | GOSR2 | Gene ID | 9570 | 9570 |
| Gene name | golgi SNAP receptor complex member 2 | golgi SNAP receptor complex member 2 | |
| Synonyms | Bos1|EPM6|GS27 | Bos1|EPM6|GS27 | |
| Cytomap | 17q21.32 | 17q21.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | Golgi SNAP receptor complex member 227 kDa Golgi SNARE proteinmembrin | Golgi SNAP receptor complex member 227 kDa Golgi SNARE proteinmembrin | |
| Modification date | 20180527 | 20180527 | |
| UniProtAcc | O14653 | O14653 | |
| Ensembl transtripts involved in fusion gene | ENST00000439730, ENST00000576910, ENST00000393456, ENST00000415811, ENST00000575949, ENST00000225567, | ENST00000439730, ENST00000576910, ENST00000393456, ENST00000415811, ENST00000575949, ENST00000225567, | |
| Fusion gene scores | * DoF score | 4 X 4 X 3=48 | 4 X 4 X 4=64 |
| # samples | 4 | 4 | |
| ** MAII score | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: GOSR2 [Title/Abstract] AND GOSR2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | GOSR2 | GO:0006888 | ER to Golgi vesicle-mediated transport | 9349823 |
| Hgene | GOSR2 | GO:0006891 | intra-Golgi vesicle-mediated transport | 9349823 |
| Tgene | GOSR2 | GO:0006888 | ER to Golgi vesicle-mediated transport | 9349823 |
| Tgene | GOSR2 | GO:0006891 | intra-Golgi vesicle-mediated transport | 9349823 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AI400943 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000439730 | ENST00000439730 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-3CDS | ENST00000439730 | ENST00000576910 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-3CDS | ENST00000439730 | ENST00000393456 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000439730 | ENST00000415811 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000439730 | ENST00000575949 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000439730 | ENST00000225567 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-3CDS | ENST00000576910 | ENST00000439730 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-3CDS | ENST00000576910 | ENST00000576910 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-3CDS | ENST00000576910 | ENST00000393456 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-intron | ENST00000576910 | ENST00000415811 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-intron | ENST00000576910 | ENST00000575949 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-intron | ENST00000576910 | ENST00000225567 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-3CDS | ENST00000393456 | ENST00000439730 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-3CDS | ENST00000393456 | ENST00000576910 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-3CDS | ENST00000393456 | ENST00000393456 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-intron | ENST00000393456 | ENST00000415811 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-intron | ENST00000393456 | ENST00000575949 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| 3UTR-intron | ENST00000393456 | ENST00000225567 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-3CDS | ENST00000415811 | ENST00000439730 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-3CDS | ENST00000415811 | ENST00000576910 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-3CDS | ENST00000415811 | ENST00000393456 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000415811 | ENST00000415811 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000415811 | ENST00000575949 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000415811 | ENST00000225567 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-3CDS | ENST00000575949 | ENST00000439730 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-3CDS | ENST00000575949 | ENST00000576910 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-3CDS | ENST00000575949 | ENST00000393456 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000575949 | ENST00000415811 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000575949 | ENST00000575949 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000575949 | ENST00000225567 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-3CDS | ENST00000225567 | ENST00000439730 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-3CDS | ENST00000225567 | ENST00000576910 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-3CDS | ENST00000225567 | ENST00000393456 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000225567 | ENST00000415811 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000225567 | ENST00000575949 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
| intron-intron | ENST00000225567 | ENST00000225567 | GOSR2 | chr17 | 45016130 | - | GOSR2 | chr17 | 45016038 | + |
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FusionProtFeatures for GOSR2_GOSR2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GOSR2 | GOSR2 |