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Fusion gene ID: 14806 |
FusionGeneSummary for GMFG_KDELR1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GMFG_KDELR1 | Fusion gene ID: 14806 | Hgene | Tgene | Gene symbol | GMFG | KDELR1 | Gene ID | 9535 | 10945 |
| Gene name | glia maturation factor gamma | KDEL endoplasmic reticulum protein retention receptor 1 | |
| Synonyms | GMF-GAMMA | ERD2|ERD2.1|HDEL|PM23 | |
| Cytomap | 19q13.2 | 19q13.33 | |
| Type of gene | protein-coding | protein-coding | |
| Description | glia maturation factor gamma | ER lumen protein-retaining receptor 1KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1KDEL receptor 1putative MAPK-activating protein PM23 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | O60234 | P24390 | |
| Ensembl transtripts involved in fusion gene | ENST00000601387, ENST00000597595, ENST00000598034, ENST00000600322, ENST00000602185, ENST00000253054, ENST00000594700, ENST00000595636, | ENST00000330720, ENST00000597017, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 2 X 3 X 1=6 |
| # samples | 1 | 3 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(3/6*10)=2.32192809488736 | |
| Context | PubMed: GMFG [Title/Abstract] AND KDELR1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BQ775128 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000601387 | ENST00000330720 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000601387 | ENST00000597017 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000597595 | ENST00000330720 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000597595 | ENST00000597017 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000598034 | ENST00000330720 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000598034 | ENST00000597017 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000600322 | ENST00000330720 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000600322 | ENST00000597017 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000602185 | ENST00000330720 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000602185 | ENST00000597017 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000253054 | ENST00000330720 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000253054 | ENST00000597017 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000594700 | ENST00000330720 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000594700 | ENST00000597017 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000595636 | ENST00000330720 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
| intron-3CDS | ENST00000595636 | ENST00000597017 | GMFG | chr19 | 39819706 | + | KDELR1 | chr19 | 48892846 | - |
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FusionProtFeatures for GMFG_KDELR1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GMFG | KDELR1 |