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Fusion gene ID: 14683 |
FusionGeneSummary for GLA_HNRNPH2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GLA_HNRNPH2 | Fusion gene ID: 14683 | Hgene | Tgene | Gene symbol | GLA | HNRNPH2 | Gene ID | 2717 | 3188 |
| Gene name | galactosidase alpha | heterogeneous nuclear ribonucleoprotein H2 | |
| Synonyms | GALA | FTP3|HNRPH'|HNRPH2|MRXSB|NRPH2|hnRNPH' | |
| Cytomap | Xq22.1 | Xq22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | alpha-galactosidase Aagalsidase alfaalpha-D-galactosidase Aalpha-D-galactoside galactohydrolase 1alpha-gal Amelibiase | heterogeneous nuclear ribonucleoprotein H2FTP-3heterogeneous nuclear ribonucleoprotein H-primeheterogeneous nuclear ribonucleoprotein H2 (H')hnRNP H'hnRNP H2 | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | P06280 | P55795 | |
| Ensembl transtripts involved in fusion gene | ENST00000218516, ENST00000479445, | ENST00000316594, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 1 X 1 X 1=1 |
| # samples | 1 | 1 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: GLA [Title/Abstract] AND HNRNPH2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | GLA | GO:0009311 | oligosaccharide metabolic process | 39940 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-S3-A6ZF-01A | GLA | chrX | 100662698 | - | HNRNPH2 | chrX | 100666924 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000218516 | ENST00000316594 | GLA | chrX | 100662698 | - | HNRNPH2 | chrX | 100666924 | + |
| 5UTR-5UTR | ENST00000479445 | ENST00000316594 | GLA | chrX | 100662698 | - | HNRNPH2 | chrX | 100666924 | + |
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FusionProtFeatures for GLA_HNRNPH2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GLA | HNRNPH2 |