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Fusion gene ID: 14349 |
FusionGeneSummary for GANC_GANC |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GANC_GANC | Fusion gene ID: 14349 | Hgene | Tgene | Gene symbol | GANC | GANC | Gene ID | 2595 | 2595 |
| Gene name | glucosidase alpha, neutral C | glucosidase alpha, neutral C | |
| Synonyms | - | - | |
| Cytomap | 15q15.1 | 15q15.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | neutral alpha-glucosidase C | neutral alpha-glucosidase C | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q8TET4 | Q8TET4 | |
| Ensembl transtripts involved in fusion gene | ENST00000566442, ENST00000318010, ENST00000440615, | ENST00000566442, ENST00000318010, ENST00000440615, | |
| Fusion gene scores | * DoF score | 3 X 3 X 3=27 | 5 X 5 X 3=75 |
| # samples | 3 | 5 | |
| ** MAII score | log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(5/75*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: GANC [Title/Abstract] AND GANC [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AW572233 | GANC | chr15 | 42645790 | - | GANC | chr15 | 42645704 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000566442 | ENST00000566442 | GANC | chr15 | 42645790 | - | GANC | chr15 | 42645704 | + |
| intron-3UTR | ENST00000566442 | ENST00000318010 | GANC | chr15 | 42645790 | - | GANC | chr15 | 42645704 | + |
| intron-intron | ENST00000566442 | ENST00000440615 | GANC | chr15 | 42645790 | - | GANC | chr15 | 42645704 | + |
| 3UTR-intron | ENST00000318010 | ENST00000566442 | GANC | chr15 | 42645790 | - | GANC | chr15 | 42645704 | + |
| 3UTR-3UTR | ENST00000318010 | ENST00000318010 | GANC | chr15 | 42645790 | - | GANC | chr15 | 42645704 | + |
| 3UTR-intron | ENST00000318010 | ENST00000440615 | GANC | chr15 | 42645790 | - | GANC | chr15 | 42645704 | + |
| intron-intron | ENST00000440615 | ENST00000566442 | GANC | chr15 | 42645790 | - | GANC | chr15 | 42645704 | + |
| intron-3UTR | ENST00000440615 | ENST00000318010 | GANC | chr15 | 42645790 | - | GANC | chr15 | 42645704 | + |
| intron-intron | ENST00000440615 | ENST00000440615 | GANC | chr15 | 42645790 | - | GANC | chr15 | 42645704 | + |
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FusionProtFeatures for GANC_GANC |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GANC | GANC |