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Fusion gene ID: 14304 |
FusionGeneSummary for GALNT14_NRXN1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GALNT14_NRXN1 | Fusion gene ID: 14304 | Hgene | Tgene | Gene symbol | GALNT14 | NRXN1 | Gene ID | 79623 | 9378 |
| Gene name | polypeptide N-acetylgalactosaminyltransferase 14 | neurexin 1 | |
| Synonyms | GALNT15|GalNac-T10|GalNac-T14 | Hs.22998|PTHSL2|SCZD17 | |
| Cytomap | 2p23.1 | 2p16.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | polypeptide N-acetylgalactosaminyltransferase 14UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T10UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 ( | neurexin-1neurexin I | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q96FL9 | Q9ULB1 | |
| Ensembl transtripts involved in fusion gene | ENST00000324589, ENST00000349752, ENST00000406653, ENST00000356174, ENST00000420311, ENST00000486564, | ENST00000342183, ENST00000401710, ENST00000404971, ENST00000406316, ENST00000405472, ENST00000401669, ENST00000406859, ENST00000402717, ENST00000331040, ENST00000405581, | |
| Fusion gene scores | * DoF score | 5 X 5 X 4=100 | 6 X 6 X 4=144 |
| # samples | 8 | 6 | |
| ** MAII score | log2(8/100*10)=-0.321928094887362 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: GALNT14 [Title/Abstract] AND NRXN1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-XK-AAJA-01A | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000324589 | ENST00000342183 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000324589 | ENST00000401710 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000324589 | ENST00000404971 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000324589 | ENST00000406316 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000324589 | ENST00000405472 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000324589 | ENST00000401669 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000324589 | ENST00000406859 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000324589 | ENST00000402717 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5CDS-intron | ENST00000324589 | ENST00000331040 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5CDS-intron | ENST00000324589 | ENST00000405581 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000349752 | ENST00000342183 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000349752 | ENST00000401710 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000349752 | ENST00000404971 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000349752 | ENST00000406316 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000349752 | ENST00000405472 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000349752 | ENST00000401669 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000349752 | ENST00000406859 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000349752 | ENST00000402717 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5CDS-intron | ENST00000349752 | ENST00000331040 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5CDS-intron | ENST00000349752 | ENST00000405581 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000406653 | ENST00000342183 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000406653 | ENST00000401710 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000406653 | ENST00000404971 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000406653 | ENST00000406316 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000406653 | ENST00000405472 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000406653 | ENST00000401669 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000406653 | ENST00000406859 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000406653 | ENST00000402717 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-intron | ENST00000406653 | ENST00000331040 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-intron | ENST00000406653 | ENST00000405581 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000356174 | ENST00000342183 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000356174 | ENST00000401710 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000356174 | ENST00000404971 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000356174 | ENST00000406316 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000356174 | ENST00000405472 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000356174 | ENST00000401669 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000356174 | ENST00000406859 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| In-frame | ENST00000356174 | ENST00000402717 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5CDS-intron | ENST00000356174 | ENST00000331040 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5CDS-intron | ENST00000356174 | ENST00000405581 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5UTR-3CDS | ENST00000420311 | ENST00000342183 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5UTR-3CDS | ENST00000420311 | ENST00000401710 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5UTR-3CDS | ENST00000420311 | ENST00000404971 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5UTR-3CDS | ENST00000420311 | ENST00000406316 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5UTR-3CDS | ENST00000420311 | ENST00000405472 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5UTR-3CDS | ENST00000420311 | ENST00000401669 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5UTR-3CDS | ENST00000420311 | ENST00000406859 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5UTR-3CDS | ENST00000420311 | ENST00000402717 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5UTR-intron | ENST00000420311 | ENST00000331040 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| 5UTR-intron | ENST00000420311 | ENST00000405581 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000486564 | ENST00000342183 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000486564 | ENST00000401710 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000486564 | ENST00000404971 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000486564 | ENST00000406316 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000486564 | ENST00000405472 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000486564 | ENST00000401669 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000486564 | ENST00000406859 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-3CDS | ENST00000486564 | ENST00000402717 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-intron | ENST00000486564 | ENST00000331040 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
| intron-intron | ENST00000486564 | ENST00000405581 | GALNT14 | chr2 | 31360824 | - | NRXN1 | chr2 | 50170929 | - |
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FusionProtFeatures for GALNT14_NRXN1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GALNT14 | NRXN1 |