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Fusion gene ID: 14303 |
FusionGeneSummary for GALNT14_LAMTOR2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GALNT14_LAMTOR2 | Fusion gene ID: 14303 | Hgene | Tgene | Gene symbol | GALNT14 | LAMTOR2 | Gene ID | 79623 | 28956 |
| Gene name | polypeptide N-acetylgalactosaminyltransferase 14 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | |
| Synonyms | GALNT15|GalNac-T10|GalNac-T14 | ENDAP|HSPC003|MAPBPIP|MAPKSP1AP|ROBLD3|Ragulator2|p14 | |
| Cytomap | 2p23.1 | 1q22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | polypeptide N-acetylgalactosaminyltransferase 14UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 14UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase T10UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 ( | ragulator complex protein LAMTOR2MAPBP-interacting proteinMAPKSP1 adaptor proteinendosomal adaptor protein p14late endosomal/lysosomal Mp1-interacting proteinlate endosomal/lysosomal adaptor and MAPK and MTOR activator 2mitogen-activated protein-bin | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q96FL9 | Q9Y2Q5 | |
| Ensembl transtripts involved in fusion gene | ENST00000324589, ENST00000349752, ENST00000406653, ENST00000356174, ENST00000420311, ENST00000486564, | ENST00000368305, ENST00000368304, ENST00000489664, ENST00000368302, | |
| Fusion gene scores | * DoF score | 5 X 5 X 4=100 | 1 X 1 X 1=1 |
| # samples | 8 | 1 | |
| ** MAII score | log2(8/100*10)=-0.321928094887362 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: GALNT14 [Title/Abstract] AND LAMTOR2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AK024039 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-5UTR | ENST00000324589 | ENST00000368305 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-5UTR | ENST00000324589 | ENST00000368304 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000324589 | ENST00000489664 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000324589 | ENST00000368302 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-5UTR | ENST00000349752 | ENST00000368305 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-5UTR | ENST00000349752 | ENST00000368304 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000349752 | ENST00000489664 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000349752 | ENST00000368302 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-5UTR | ENST00000406653 | ENST00000368305 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-5UTR | ENST00000406653 | ENST00000368304 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000406653 | ENST00000489664 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000406653 | ENST00000368302 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-5UTR | ENST00000356174 | ENST00000368305 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-5UTR | ENST00000356174 | ENST00000368304 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000356174 | ENST00000489664 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000356174 | ENST00000368302 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-5UTR | ENST00000420311 | ENST00000368305 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-5UTR | ENST00000420311 | ENST00000368304 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000420311 | ENST00000489664 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000420311 | ENST00000368302 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-5UTR | ENST00000486564 | ENST00000368305 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-5UTR | ENST00000486564 | ENST00000368304 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000486564 | ENST00000489664 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
| intron-intron | ENST00000486564 | ENST00000368302 | GALNT14 | chr2 | 31147064 | - | LAMTOR2 | chr1 | 156024587 | + |
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FusionProtFeatures for GALNT14_LAMTOR2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GALNT14 | LAMTOR2 |