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Fusion gene ID: 14209 |
FusionGeneSummary for GABARAPL1_GIGYF2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: GABARAPL1_GIGYF2 | Fusion gene ID: 14209 | Hgene | Tgene | Gene symbol | GABARAPL1 | GIGYF2 | Gene ID | 23710 | 26058 |
| Gene name | GABA type A receptor associated protein like 1 | GRB10 interacting GYF protein 2 | |
| Synonyms | APG8-LIKE|APG8L|ATG8|ATG8B|ATG8L|GEC1 | GYF2|PARK11|PERQ2|PERQ3|TNRC15 | |
| Cytomap | 12p13.2 | 2q37.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | gamma-aminobutyric acid receptor-associated protein-like 1GABA(A) receptor-associated protein-like 1early estrogen-regulated proteinglandular epithelial cell protein 1 | GRB10-interacting GYF protein 2PERQ amino acid rich, with GYF domain 3PERQ amino acid-rich with GYF domain-containing protein 2Parkinson disease (autosomal recessive, early onset) 11trinucleotide repeat-containing gene 15 protein | |
| Modification date | 20180524 | 20180522 | |
| UniProtAcc | Q9H0R8 | Q6Y7W6 | |
| Ensembl transtripts involved in fusion gene | ENST00000266458, ENST00000421801, ENST00000544284, ENST00000545047, ENST00000543602, ENST00000545887, ENST00000539289, ENST00000546017, ENST00000535576, ENST00000539170, | ENST00000373566, ENST00000373563, ENST00000409480, ENST00000409547, ENST00000409196, ENST00000409451, ENST00000482666, ENST00000452341, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 10 X 12 X 4=480 |
| # samples | 1 | 13 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(13/480*10)=-1.88452278258006 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: GABARAPL1 [Title/Abstract] AND GIGYF2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | GIGYF2 | GO:0016441 | posttranscriptional gene silencing | 27157137 |
| Tgene | GIGYF2 | GO:0061157 | mRNA destabilization | 27157137 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AI215508 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-intron | ENST00000266458 | ENST00000373566 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000266458 | ENST00000373563 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000266458 | ENST00000409480 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000266458 | ENST00000409547 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000266458 | ENST00000409196 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000266458 | ENST00000409451 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000266458 | ENST00000482666 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000266458 | ENST00000452341 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000421801 | ENST00000373566 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000421801 | ENST00000373563 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000421801 | ENST00000409480 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000421801 | ENST00000409547 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000421801 | ENST00000409196 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000421801 | ENST00000409451 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000421801 | ENST00000482666 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000421801 | ENST00000452341 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000544284 | ENST00000373566 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000544284 | ENST00000373563 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000544284 | ENST00000409480 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000544284 | ENST00000409547 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000544284 | ENST00000409196 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000544284 | ENST00000409451 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000544284 | ENST00000482666 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000544284 | ENST00000452341 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545047 | ENST00000373566 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545047 | ENST00000373563 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545047 | ENST00000409480 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545047 | ENST00000409547 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545047 | ENST00000409196 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545047 | ENST00000409451 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545047 | ENST00000482666 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545047 | ENST00000452341 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000543602 | ENST00000373566 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000543602 | ENST00000373563 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000543602 | ENST00000409480 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000543602 | ENST00000409547 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000543602 | ENST00000409196 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000543602 | ENST00000409451 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000543602 | ENST00000482666 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000543602 | ENST00000452341 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545887 | ENST00000373566 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545887 | ENST00000373563 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545887 | ENST00000409480 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545887 | ENST00000409547 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545887 | ENST00000409196 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545887 | ENST00000409451 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545887 | ENST00000482666 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000545887 | ENST00000452341 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000539289 | ENST00000373566 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000539289 | ENST00000373563 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000539289 | ENST00000409480 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000539289 | ENST00000409547 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000539289 | ENST00000409196 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000539289 | ENST00000409451 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000539289 | ENST00000482666 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000539289 | ENST00000452341 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000546017 | ENST00000373566 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000546017 | ENST00000373563 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000546017 | ENST00000409480 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000546017 | ENST00000409547 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000546017 | ENST00000409196 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000546017 | ENST00000409451 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000546017 | ENST00000482666 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000546017 | ENST00000452341 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000535576 | ENST00000373566 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000535576 | ENST00000373563 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000535576 | ENST00000409480 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000535576 | ENST00000409547 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000535576 | ENST00000409196 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000535576 | ENST00000409451 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000535576 | ENST00000482666 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| intron-intron | ENST00000535576 | ENST00000452341 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000539170 | ENST00000373566 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000539170 | ENST00000373563 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000539170 | ENST00000409480 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000539170 | ENST00000409547 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000539170 | ENST00000409196 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000539170 | ENST00000409451 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000539170 | ENST00000482666 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
| 3UTR-intron | ENST00000539170 | ENST00000452341 | GABARAPL1 | chr12 | 10375604 | - | GIGYF2 | chr2 | 233621063 | - |
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FusionProtFeatures for GABARAPL1_GIGYF2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| GABARAPL1 | GIGYF2 |