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Fusion gene ID: 14184 |
FusionGeneSummary for G3BP2_NAAA |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: G3BP2_NAAA | Fusion gene ID: 14184 | Hgene | Tgene | Gene symbol | G3BP2 | NAAA | Gene ID | 9908 | 27163 |
| Gene name | G3BP stress granule assembly factor 2 | N-acylethanolamine acid amidase | |
| Synonyms | - | ASAHL|PLT | |
| Cytomap | 4q21.1 | 4q21.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ras GTPase-activating protein-binding protein 2G3BP-2GAP SH3 domain-binding protein 2GTPase activating protein (SH3 domain) binding protein 2Ras-GTPase activating protein SH3 domain-binding protein 2 | N-acylethanolamine-hydrolyzing acid amidaseASAH-like proteinacid ceramidase-like protein | |
| Modification date | 20180523 | 20180529 | |
| UniProtAcc | Q9UN86 | Q02083 | |
| Ensembl transtripts involved in fusion gene | ENST00000395719, ENST00000359707, ENST00000357854, ENST00000502654, | ENST00000399497, ENST00000286733, ENST00000511606, ENST00000507956, ENST00000505594, ENST00000507187, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 2 X 3 X 2=12 |
| # samples | 2 | 3 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: G3BP2 [Title/Abstract] AND NAAA [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-44-7660-01A | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000395719 | ENST00000399497 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| intron-3CDS | ENST00000395719 | ENST00000286733 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| intron-5UTR | ENST00000395719 | ENST00000511606 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| intron-5UTR | ENST00000395719 | ENST00000507956 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| intron-5UTR | ENST00000395719 | ENST00000505594 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| intron-intron | ENST00000395719 | ENST00000507187 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-3CDS | ENST00000359707 | ENST00000399497 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-3CDS | ENST00000359707 | ENST00000286733 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-5UTR | ENST00000359707 | ENST00000511606 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-5UTR | ENST00000359707 | ENST00000507956 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-5UTR | ENST00000359707 | ENST00000505594 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-intron | ENST00000359707 | ENST00000507187 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-3CDS | ENST00000357854 | ENST00000399497 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-3CDS | ENST00000357854 | ENST00000286733 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-5UTR | ENST00000357854 | ENST00000511606 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-5UTR | ENST00000357854 | ENST00000507956 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-5UTR | ENST00000357854 | ENST00000505594 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-intron | ENST00000357854 | ENST00000507187 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-3CDS | ENST00000502654 | ENST00000399497 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-3CDS | ENST00000502654 | ENST00000286733 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-5UTR | ENST00000502654 | ENST00000511606 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-5UTR | ENST00000502654 | ENST00000507956 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-5UTR | ENST00000502654 | ENST00000505594 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
| 5UTR-intron | ENST00000502654 | ENST00000507187 | G3BP2 | chr4 | 76598392 | - | NAAA | chr4 | 76841128 | - |
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FusionProtFeatures for G3BP2_NAAA |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| G3BP2 | NAAA |