|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 13985 |
FusionGeneSummary for FRYL_FAM19A2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FRYL_FAM19A2 | Fusion gene ID: 13985 | Hgene | Tgene | Gene symbol | FRYL | FAM19A2 | Gene ID | 285527 | 338811 |
| Gene name | FRY like transcription coactivator | family with sequence similarity 19 member A2, C-C motif chemokine like | |
| Synonyms | AF4p12|KIAA0826|MOR2 | TAFA-2|TAFA2 | |
| Cytomap | 4p11 | 12q14.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein furry homolog-likeALL1-fused gene from chromosome 4p12 proteinFRY-likefurry homolog-likefurry-likemor2 cell polarity protein homolog | protein FAM19A2chemokine-like protein TAFA-2family with sequence similarity 19 (chemokine (C-C motif)-like), member A2 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | O94915 | Q8N3H0 | |
| Ensembl transtripts involved in fusion gene | ENST00000503238, ENST00000358350, ENST00000537810, ENST00000264319, ENST00000507711, ENST00000514783, ENST00000507873, ENST00000506685, | ENST00000416284, ENST00000551619, ENST00000550003, ENST00000551449, ENST00000549456, | |
| Fusion gene scores | * DoF score | 14 X 11 X 11=1694 | 11 X 6 X 5=330 |
| # samples | 21 | 10 | |
| ** MAII score | log2(21/1694*10)=-3.01197264166608 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(10/330*10)=-1.72246602447109 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FRYL [Title/Abstract] AND FAM19A2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | STAD | TCGA-CG-4476-01A | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000503238 | ENST00000416284 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-5UTR | ENST00000503238 | ENST00000551619 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-intron | ENST00000503238 | ENST00000550003 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-5UTR | ENST00000503238 | ENST00000551449 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-intron | ENST00000503238 | ENST00000549456 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-5UTR | ENST00000358350 | ENST00000416284 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-5UTR | ENST00000358350 | ENST00000551619 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-intron | ENST00000358350 | ENST00000550003 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-5UTR | ENST00000358350 | ENST00000551449 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-intron | ENST00000358350 | ENST00000549456 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-5UTR | ENST00000537810 | ENST00000416284 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-5UTR | ENST00000537810 | ENST00000551619 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-intron | ENST00000537810 | ENST00000550003 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-5UTR | ENST00000537810 | ENST00000551449 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-intron | ENST00000537810 | ENST00000549456 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5UTR-5UTR | ENST00000264319 | ENST00000416284 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5UTR-5UTR | ENST00000264319 | ENST00000551619 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5UTR-intron | ENST00000264319 | ENST00000550003 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5UTR-5UTR | ENST00000264319 | ENST00000551449 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5UTR-intron | ENST00000264319 | ENST00000549456 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-5UTR | ENST00000507711 | ENST00000416284 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-5UTR | ENST00000507711 | ENST00000551619 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-intron | ENST00000507711 | ENST00000550003 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-5UTR | ENST00000507711 | ENST00000551449 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| 5CDS-intron | ENST00000507711 | ENST00000549456 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-5UTR | ENST00000514783 | ENST00000416284 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-5UTR | ENST00000514783 | ENST00000551619 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-intron | ENST00000514783 | ENST00000550003 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-5UTR | ENST00000514783 | ENST00000551449 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-intron | ENST00000514783 | ENST00000549456 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-5UTR | ENST00000507873 | ENST00000416284 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-5UTR | ENST00000507873 | ENST00000551619 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-intron | ENST00000507873 | ENST00000550003 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-5UTR | ENST00000507873 | ENST00000551449 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-intron | ENST00000507873 | ENST00000549456 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-5UTR | ENST00000506685 | ENST00000416284 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-5UTR | ENST00000506685 | ENST00000551619 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-intron | ENST00000506685 | ENST00000550003 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-5UTR | ENST00000506685 | ENST00000551449 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
| intron-intron | ENST00000506685 | ENST00000549456 | FRYL | chr4 | 48636308 | - | FAM19A2 | chr12 | 62261207 | - |
Top |
FusionProtFeatures for FRYL_FAM19A2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FRYL | FAM19A2 |