	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 13764

FusionGeneSummary for FOXJ3_TUFT1

Fusion gene summary

Fusion gene information	Fusion gene name: FOXJ3_TUFT1
	Fusion gene ID: 13764
		Hgene	Tgene
	Gene symbol	FOXJ3	TUFT1
	Gene ID	22887	7286
	Gene name	forkhead box J3	tuftelin 1
	Synonyms	-	-
	Cytomap	1p34.2	1q21.3
	Type of gene	protein-coding	protein-coding
	Description	forkhead box protein J3	tuftelin
	Modification date	20180522	20180523
	UniProtAcc	Q9UPW0	Q9NNX1
	Ensembl transtripts involved in fusion gene	ENST00000372572, ENST00000372573, ENST00000361346, ENST00000361776, ENST00000545068, ENST00000372571,	ENST00000353024, ENST00000392712, ENST00000368849, ENST00000368848, ENST00000538902,
Fusion gene scores	* DoF score	14 X 9 X 11=1386	5 X 4 X 3=60
	# samples	16	5
	** MAII score	log2(16/1386*10)=-3.11478344724985 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: FOXJ3 [Title/Abstract] AND TUFT1 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	FOXJ3	GO:0045944	positive regulation of transcription by RNA polymerase II	22740631

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
TCGA	LD	UCEC	TCGA-BK-A26L-01A	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000372572	ENST00000353024	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000372572	ENST00000392712	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000372572	ENST00000368849	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000372572	ENST00000368848	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000372572	ENST00000538902	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000372573	ENST00000353024	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000372573	ENST00000392712	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000372573	ENST00000368849	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000372573	ENST00000368848	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000372573	ENST00000538902	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000361346	ENST00000353024	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000361346	ENST00000392712	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000361346	ENST00000368849	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000361346	ENST00000368848	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000361346	ENST00000538902	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000361776	ENST00000353024	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000361776	ENST00000392712	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000361776	ENST00000368849	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000361776	ENST00000368848	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000361776	ENST00000538902	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000545068	ENST00000353024	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000545068	ENST00000392712	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000545068	ENST00000368849	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000545068	ENST00000368848	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
5CDS-intron	ENST00000545068	ENST00000538902	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
intron-intron	ENST00000372571	ENST00000353024	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
intron-intron	ENST00000372571	ENST00000392712	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
intron-intron	ENST00000372571	ENST00000368849	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
intron-intron	ENST00000372571	ENST00000368848	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+
intron-intron	ENST00000372571	ENST00000538902	FOXJ3	chr1	42744019	-	TUFT1	chr1	151535061	+

Top

FusionProtFeatures for FOXJ3_TUFT1

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
FOXJ3 Q9UPW0	TUFT1 Q9NNX1

Home

Download

Statistics

Examples

Help

Contact

Fusion gene ID: 13764

FusionGeneSummary for FOXJ3_TUFT1

FusionProtFeatures for FOXJ3_TUFT1