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Fusion gene ID: 13496 |
FusionGeneSummary for FKBP11_TENM3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FKBP11_TENM3 | Fusion gene ID: 13496 | Hgene | Tgene | Gene symbol | FKBP11 | TENM3 | Gene ID | 51303 | 55714 |
| Gene name | FK506 binding protein 11 | teneurin transmembrane protein 3 | |
| Synonyms | FKBP19 | MCOPCB9|ODZ3|TNM3|Ten-m3|ten-3 | |
| Cytomap | 12q13.12 | 4q34.3-q35.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | peptidyl-prolyl cis-trans isomerase FKBP1119 kDa FK506-binding protein19 kDa FKBPFK506 binding protein 11, 19 kDaFKBP-11FKBP-19PPIase FKBP11rotamase | teneurin-3ODZ3-like proteinodz, odd Oz/ten-m homolog 3protein Odd Oz/ten-m homolog 3tenascin-M3testicular tissue protein Li 195 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q9NYL4 | Q9P273 | |
| Ensembl transtripts involved in fusion gene | ENST00000444214, ENST00000550765, ENST00000552878, ENST00000453172, | ENST00000511685, ENST00000406950, ENST00000502950, | |
| Fusion gene scores | * DoF score | 3 X 3 X 2=18 | 4 X 4 X 2=32 |
| # samples | 3 | 4 | |
| ** MAII score | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: FKBP11 [Title/Abstract] AND TENM3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BF964329 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3UTR | ENST00000444214 | ENST00000511685 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| intron-intron | ENST00000444214 | ENST00000406950 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| intron-intron | ENST00000444214 | ENST00000502950 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| intron-3UTR | ENST00000550765 | ENST00000511685 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| intron-intron | ENST00000550765 | ENST00000406950 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| intron-intron | ENST00000550765 | ENST00000502950 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| intron-3UTR | ENST00000552878 | ENST00000511685 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| intron-intron | ENST00000552878 | ENST00000406950 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| intron-intron | ENST00000552878 | ENST00000502950 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| intron-3UTR | ENST00000453172 | ENST00000511685 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| intron-intron | ENST00000453172 | ENST00000406950 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
| intron-intron | ENST00000453172 | ENST00000502950 | FKBP11 | chr12 | 49316146 | + | TENM3 | chr4 | 183723933 | + |
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FusionProtFeatures for FKBP11_TENM3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FKBP11 | TENM3 |