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Fusion gene ID: 1340 |
FusionGeneSummary for AKAP3_AKAP3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: AKAP3_AKAP3 | Fusion gene ID: 1340 | Hgene | Tgene | Gene symbol | AKAP3 | AKAP3 | Gene ID | 10566 | 10566 |
| Gene name | A-kinase anchoring protein 3 | A-kinase anchoring protein 3 | |
| Synonyms | AKAP 110|AKAP110|CT82|FSP95|HEL159|PRKA3|SOB1 | AKAP 110|AKAP110|CT82|FSP95|HEL159|PRKA3|SOB1 | |
| Cytomap | 12p13.32 | 12p13.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | A-kinase anchor protein 3A kinase (PRKA) anchor protein 3A-kinase anchor protein, 110kDaFibrous Sheath Protein of 95 kDacancer/testis antigen 82epididymis luminal protein 159fibrousheathin Ifibrousheathin-1protein kinase A binding protein AKAP 110 | A-kinase anchor protein 3A kinase (PRKA) anchor protein 3A-kinase anchor protein, 110kDaFibrous Sheath Protein of 95 kDacancer/testis antigen 82epididymis luminal protein 159fibrousheathin Ifibrousheathin-1protein kinase A binding protein AKAP 110 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | O75969 | O75969 | |
| Ensembl transtripts involved in fusion gene | ENST00000545990, ENST00000228850, ENST00000544636, | ENST00000545990, ENST00000228850, ENST00000544636, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 1 X 1 X 1=1 |
| # samples | 1 | 1 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: AKAP3 [Title/Abstract] AND AKAP3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | AW512277 | AKAP3 | chr12 | 4724791 | + | AKAP3 | chr12 | 4725062 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000545990 | ENST00000545990 | AKAP3 | chr12 | 4724791 | + | AKAP3 | chr12 | 4725062 | - |
| intron-3CDS | ENST00000545990 | ENST00000228850 | AKAP3 | chr12 | 4724791 | + | AKAP3 | chr12 | 4725062 | - |
| intron-intron | ENST00000545990 | ENST00000544636 | AKAP3 | chr12 | 4724791 | + | AKAP3 | chr12 | 4725062 | - |
| intron-3CDS | ENST00000228850 | ENST00000545990 | AKAP3 | chr12 | 4724791 | + | AKAP3 | chr12 | 4725062 | - |
| intron-3CDS | ENST00000228850 | ENST00000228850 | AKAP3 | chr12 | 4724791 | + | AKAP3 | chr12 | 4725062 | - |
| intron-intron | ENST00000228850 | ENST00000544636 | AKAP3 | chr12 | 4724791 | + | AKAP3 | chr12 | 4725062 | - |
| intron-3CDS | ENST00000544636 | ENST00000545990 | AKAP3 | chr12 | 4724791 | + | AKAP3 | chr12 | 4725062 | - |
| intron-3CDS | ENST00000544636 | ENST00000228850 | AKAP3 | chr12 | 4724791 | + | AKAP3 | chr12 | 4725062 | - |
| intron-intron | ENST00000544636 | ENST00000544636 | AKAP3 | chr12 | 4724791 | + | AKAP3 | chr12 | 4725062 | - |
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FusionProtFeatures for AKAP3_AKAP3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| AKAP3 | AKAP3 |