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Fusion gene ID: 12696 |
FusionGeneSummary for FAM198B_IGKJ1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FAM198B_IGKJ1 | Fusion gene ID: 12696 | Hgene | Tgene | Gene symbol | FAM198B | IGKJ1 | Gene ID | 51313 | 28950 |
| Gene name | family with sequence similarity 198 member B | immunoglobulin kappa joining 1 | |
| Synonyms | AD021|AD036|C4orf18|ENED | J1 | |
| Cytomap | 4q32.1 | 2p11.2 | |
| Type of gene | protein-coding | other | |
| Description | protein FAM198Bexpressed in nerve and epithelium during development | - | |
| Modification date | 20180403 | 20180429 | |
| UniProtAcc | Q6UWH4 | ||
| Ensembl transtripts involved in fusion gene | ENST00000585682, ENST00000296530, ENST00000393807, ENST00000589306, ENST00000592057, | ENST00000390242, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 7 X 5 X 5=175 |
| # samples | 1 | 7 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(7/175*10)=-1.32192809488736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FAM198B [Title/Abstract] AND IGKJ1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-13-1481-01A | FAM198B | chr4 | 159046787 | - | IGKJ1 | chr2 | 89161431 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000585682 | ENST00000390242 | FAM198B | chr4 | 159046787 | - | IGKJ1 | chr2 | 89161431 | - |
| intron-3CDS | ENST00000296530 | ENST00000390242 | FAM198B | chr4 | 159046787 | - | IGKJ1 | chr2 | 89161431 | - |
| intron-3CDS | ENST00000393807 | ENST00000390242 | FAM198B | chr4 | 159046787 | - | IGKJ1 | chr2 | 89161431 | - |
| intron-3CDS | ENST00000589306 | ENST00000390242 | FAM198B | chr4 | 159046787 | - | IGKJ1 | chr2 | 89161431 | - |
| intron-3CDS | ENST00000592057 | ENST00000390242 | FAM198B | chr4 | 159046787 | - | IGKJ1 | chr2 | 89161431 | - |
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FusionProtFeatures for FAM198B_IGKJ1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FAM198B | IGKJ1 |