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Fusion gene ID: 12482 |
FusionGeneSummary for FAM114A1_FAM114A1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: FAM114A1_FAM114A1 | Fusion gene ID: 12482 | Hgene | Tgene | Gene symbol | FAM114A1 | FAM114A1 | Gene ID | 92689 | 92689 |
| Gene name | family with sequence similarity 114 member A1 | family with sequence similarity 114 member A1 | |
| Synonyms | Noxp20 | Noxp20 | |
| Cytomap | 4p14 | 4p14 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein NOXP20nervous system over-expressed protein 20 | protein NOXP20nervous system over-expressed protein 20 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q8IWE2 | Q8IWE2 | |
| Ensembl transtripts involved in fusion gene | ENST00000515037, ENST00000358869, ENST00000513966, | ENST00000515037, ENST00000358869, ENST00000513966, | |
| Fusion gene scores | * DoF score | 8 X 7 X 6=336 | 4 X 3 X 4=48 |
| # samples | 8 | 4 | |
| ** MAII score | log2(8/336*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: FAM114A1 [Title/Abstract] AND FAM114A1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS3.1 | BE928450 | FAM114A1 | chr4 | 38916168 | - | FAM114A1 | chr4 | 38931746 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-intron | ENST00000515037 | ENST00000515037 | FAM114A1 | chr4 | 38916168 | - | FAM114A1 | chr4 | 38931746 | + |
| intron-intron | ENST00000515037 | ENST00000358869 | FAM114A1 | chr4 | 38916168 | - | FAM114A1 | chr4 | 38931746 | + |
| intron-intron | ENST00000515037 | ENST00000513966 | FAM114A1 | chr4 | 38916168 | - | FAM114A1 | chr4 | 38931746 | + |
| intron-intron | ENST00000358869 | ENST00000515037 | FAM114A1 | chr4 | 38916168 | - | FAM114A1 | chr4 | 38931746 | + |
| intron-intron | ENST00000358869 | ENST00000358869 | FAM114A1 | chr4 | 38916168 | - | FAM114A1 | chr4 | 38931746 | + |
| intron-intron | ENST00000358869 | ENST00000513966 | FAM114A1 | chr4 | 38916168 | - | FAM114A1 | chr4 | 38931746 | + |
| intron-intron | ENST00000513966 | ENST00000515037 | FAM114A1 | chr4 | 38916168 | - | FAM114A1 | chr4 | 38931746 | + |
| intron-intron | ENST00000513966 | ENST00000358869 | FAM114A1 | chr4 | 38916168 | - | FAM114A1 | chr4 | 38931746 | + |
| intron-intron | ENST00000513966 | ENST00000513966 | FAM114A1 | chr4 | 38916168 | - | FAM114A1 | chr4 | 38931746 | + |
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FusionProtFeatures for FAM114A1_FAM114A1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| FAM114A1 | FAM114A1 |